Madhya Pradesh Medical Science University,
Jabalpur
MBBS Second Professional Examination April-
2024
Subject- Pharmacology
Time: 3:00 Hours
Maximum Marks :100
Instructions:
a) All questions are compulsory
c) Answers of Questions and Sub-questions must be
written strictly according to serial order of question
paper.
d) MCQ has to be answered in theory answer book
with black or blue pen in brackets; for example: - 1.
(a) 2. (c)
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
counted in marks and action will be taken according to
UFM rules of university.
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
Q1. Total MCQs: 10
1) For which of the following drugs a warning is written
"To be sold by retail on the prescription of a Registered
Medical Practitioner only"? 10 x 1 = 10
Schedule J
2) Essential medicines are those medicines:
(a) That are needed to treat emergency conditions
(b) That are needed to treat serious diseases
population
(d) That are introduced recently into the market
3) Which of the following agent is beneficial in NSAID
induced gastric ulcer?
(d) PGF2a agonist
4) The success of oral rehydration therapy of diarrhea,
depends upon which of the following process in the
intestinal mucosa?
absorption
(c) Bicarbonate coupled Na+ absorption (d) Passive
sodium diffusion secondary to nutrient absorption
5) The most important action of beta-blockers in
(a) Membrane stabilizing effect (b) Retinal neuron
protecting effect
(c) Decrease production of aqueous humor (d) Pupillary
constriction
department after an accidental exposure to parathion.
Which of the following drugs can be given to increase the
activity of his acetyl cholinesterase?
(a) Atropine (b) Dimercaprol (c) Physostigmine (d)
7) Drug used in treatment of torsade de pointes:
(a) Quinidine (b) Amiodarone (c) Isoprenaline (d)
Verapamil
8) In a patient with hypertriglyceridemia and low HDL,
myocardial side effect?
(a) Fibric acid derivatives (b) Nicotinic acid (c)
Atorvastatin (d) Clofibrate
9) A patient of bronchial asthma was prescribed 2 puffs
following should NOT be done?
(a) Shake the inhaler well before use (b) Clean the
inhaler after every use
(c) Wait for 1 minute in between puffs (d) Rinse mouth
10) A 30 years old pregnant woman has a history of
rheumatoid arthritis which has been managed successfully
with NSAIDs. However, she has recently visited her
general practitioner complaining of burning epigastric
pain worsened by food intake. Which of the following
ulcer Medications is most likely contraindicated in this
patient?
(a) Famotidine (b) Omeprazole (c) Misoprostol (d)
Ranitidine
a. A 35-year-old woman was taking combined oral
contraceptive pills. She was diagnosed as a case of
Pulmonary tuberculosis and put on isoniazid, rifampicin,
pyrazinamide and ethambutol combination therapy daily
weekly for 4 months. In the 3rd month of treatment, she
failed to have withdrawal bleeding during the gap period
of contraceptive cycle. Later her urinary pregnancy test
was found positive.
II Explain Phase I biotransformation reaction with suitable
examples.
III Explain Microsomal Enzyme Induction.
IV Explain microsomal enzyme inhibition with suitable
b. A 70 years old male presented with complaints of weak
stream of urine, sense of incomplete voiding and increased
urinary frequency. On physical examination and
ultrasound, he was diagnosed as having benign prostatic
I Enumerate 05 drugs used in the treatment of benign
prostatic hyperplasia (BPH).
II What is the rationale of using these drugs in benign
prostatic hyperplasia (BPH).
effects of these drugs.
IV What is the role of finasteride in the treatment of
benign prostatic hyperplasia (BPH)
Q3. Brief Answer Questions
therapeutic uses. Mention first line Anti H. pylori
regimen. 6 x 05 = 30
b. Treatment of status asthmaticus.
c. Enumerate parenteral iron preparations. Mention in
route.
d. Classify Anti-Hypertensive Drugs. Enumerate drug
used in hypertension during pregnancy.
e. Classify loop diuretics. Enumerate therapeutic uses and
f. Classify various dosage forms of drug. Write in brief
about Tablets.
Q4. Short Answer Questions
a. Enumerate 04 therapeutic uses of centrally acting
b. Post marketing surveillance study.
c. Enumerate 02 differences between first and zero order
kinetics.
d. Explain, why low dose of aspirin is used for
e. Name two anti-secretory anti motility drug for
treatment of diarrhea.
f. Explain pharmacological basis of combination of
Calcium and Magnesium salts in most of antacid
g. Enumerate 2 drugs used in the treatment of productive
cough.
h. Role of nitrates in cyanide poisoning.
i. Enumerate 04 therapeutic uses of Fibrinolytics.
***
Jabalpur
MBBS Second Professional Examination April-
2024
Subject- Pharmacology
--- Content provided by FirstRanker.com ---
Paper-I (new scheme)Time: 3:00 Hours
Maximum Marks :100
Instructions:
a) All questions are compulsory
--- Content provided by FirstRanker.com ---
b) Draw diagrams wherever necessaryc) Answers of Questions and Sub-questions must be
written strictly according to serial order of question
paper.
d) MCQ has to be answered in theory answer book
--- Content provided by FirstRanker.com ---
e) Please write MCQ answer neatly and in serial orderwith black or blue pen in brackets; for example: - 1.
(a) 2. (c)
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
--- Content provided by FirstRanker.com ---
considered as malpractice, such answers will not becounted in marks and action will be taken according to
UFM rules of university.
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
--- Content provided by FirstRanker.com ---
marks should answered in up to 60 marks.Q1. Total MCQs: 10
1) For which of the following drugs a warning is written
"To be sold by retail on the prescription of a Registered
Medical Practitioner only"? 10 x 1 = 10
--- Content provided by FirstRanker.com ---
(a) Schedule H (b) Schedule X (c) Schedule Y (d)Schedule J
2) Essential medicines are those medicines:
(a) That are needed to treat emergency conditions
(b) That are needed to treat serious diseases
--- Content provided by FirstRanker.com ---
(c) That satisfy the priority health care needs of thepopulation
(d) That are introduced recently into the market
3) Which of the following agent is beneficial in NSAID
induced gastric ulcer?
--- Content provided by FirstRanker.com ---
(a) PGE1 agonist (b) PGE2 agonist (c) PGD2 agonist(d) PGF2a agonist
4) The success of oral rehydration therapy of diarrhea,
depends upon which of the following process in the
intestinal mucosa?
--- Content provided by FirstRanker.com ---
(a) Na+ absorption by Na+ (b) Glucose coupled Na+absorption
(c) Bicarbonate coupled Na+ absorption (d) Passive
sodium diffusion secondary to nutrient absorption
5) The most important action of beta-blockers in
--- Content provided by FirstRanker.com ---
glaucoma is which of the following:(a) Membrane stabilizing effect (b) Retinal neuron
protecting effect
(c) Decrease production of aqueous humor (d) Pupillary
constriction
--- Content provided by FirstRanker.com ---
6) A 24-years-old farm worker is rushed to emergencydepartment after an accidental exposure to parathion.
Which of the following drugs can be given to increase the
activity of his acetyl cholinesterase?
(a) Atropine (b) Dimercaprol (c) Physostigmine (d)
--- Content provided by FirstRanker.com ---
Pralidoxime7) Drug used in treatment of torsade de pointes:
(a) Quinidine (b) Amiodarone (c) Isoprenaline (d)
Verapamil
8) In a patient with hypertriglyceridemia and low HDL,
--- Content provided by FirstRanker.com ---
which of the following drug will be best without risk ofmyocardial side effect?
(a) Fibric acid derivatives (b) Nicotinic acid (c)
Atorvastatin (d) Clofibrate
9) A patient of bronchial asthma was prescribed 2 puffs
--- Content provided by FirstRanker.com ---
from a metered dose inhaler of budesonide. Which of thefollowing should NOT be done?
(a) Shake the inhaler well before use (b) Clean the
inhaler after every use
(c) Wait for 1 minute in between puffs (d) Rinse mouth
--- Content provided by FirstRanker.com ---
after every use10) A 30 years old pregnant woman has a history of
rheumatoid arthritis which has been managed successfully
with NSAIDs. However, she has recently visited her
general practitioner complaining of burning epigastric
--- Content provided by FirstRanker.com ---
pain worsened by food intake. Which of the following
ulcer Medications is most likely contraindicated in this
patient?
(a) Famotidine (b) Omeprazole (c) Misoprostol (d)
Ranitidine
--- Content provided by FirstRanker.com ---
Q2. Long Answer Questionsa. A 35-year-old woman was taking combined oral
contraceptive pills. She was diagnosed as a case of
Pulmonary tuberculosis and put on isoniazid, rifampicin,
pyrazinamide and ethambutol combination therapy daily
--- Content provided by FirstRanker.com ---
for 2 months followed by isoniazid and rifampicin thriceweekly for 4 months. In the 3rd month of treatment, she
failed to have withdrawal bleeding during the gap period
of contraceptive cycle. Later her urinary pregnancy test
was found positive.
--- Content provided by FirstRanker.com ---
I What is the reason for contraceptive failure?II Explain Phase I biotransformation reaction with suitable
examples.
III Explain Microsomal Enzyme Induction.
IV Explain microsomal enzyme inhibition with suitable
--- Content provided by FirstRanker.com ---
examples. 2 x 20 = 40b. A 70 years old male presented with complaints of weak
stream of urine, sense of incomplete voiding and increased
urinary frequency. On physical examination and
ultrasound, he was diagnosed as having benign prostatic
--- Content provided by FirstRanker.com ---
hyperplasia.I Enumerate 05 drugs used in the treatment of benign
prostatic hyperplasia (BPH).
II What is the rationale of using these drugs in benign
prostatic hyperplasia (BPH).
--- Content provided by FirstRanker.com ---
III Write down the mechanism of action and common sideeffects of these drugs.
IV What is the role of finasteride in the treatment of
benign prostatic hyperplasia (BPH)
Q3. Brief Answer Questions
--- Content provided by FirstRanker.com ---
a. Enumerate Proton pump inhibitors with theirtherapeutic uses. Mention first line Anti H. pylori
regimen. 6 x 05 = 30
b. Treatment of status asthmaticus.
c. Enumerate parenteral iron preparations. Mention in
--- Content provided by FirstRanker.com ---
which condition iron therapy be administered by injectionroute.
d. Classify Anti-Hypertensive Drugs. Enumerate drug
used in hypertension during pregnancy.
e. Classify loop diuretics. Enumerate therapeutic uses and
--- Content provided by FirstRanker.com ---
adverse effects of loop diuretics.f. Classify various dosage forms of drug. Write in brief
about Tablets.
Q4. Short Answer Questions
a. Enumerate 04 therapeutic uses of centrally acting
--- Content provided by FirstRanker.com ---
skeletal muscle relaxants. 10 x 2 = 20b. Post marketing surveillance study.
c. Enumerate 02 differences between first and zero order
kinetics.
d. Explain, why low dose of aspirin is used for
--- Content provided by FirstRanker.com ---
myocardial infarction?e. Name two anti-secretory anti motility drug for
treatment of diarrhea.
f. Explain pharmacological basis of combination of
Calcium and Magnesium salts in most of antacid
--- Content provided by FirstRanker.com ---
preparations.g. Enumerate 2 drugs used in the treatment of productive
cough.
h. Role of nitrates in cyanide poisoning.
i. Enumerate 04 therapeutic uses of Fibrinolytics.
--- Content provided by FirstRanker.com ---
j. Mechanism of action of osmotic diuretics.***