Jabalpur
MBBS Second Professional Examination 2022
Subject- Pharmacology
Paper- II
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Time: 3:00 HoursMaximum Marks :100
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
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c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question paper.
d) Do not write anything on the blank portion of question
paper, if written anything such type of act will be
considered as an attempt to resort to unfair means
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Long Answer questions 2 X 10 = 20Q1.
a. (i) Classify anti-malarial drugs.
(ii) Mechanism of action and Pharmacological actions
of chloroquine.
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(iii) Therapeutic uses and adverse effects ofchloroquine.
b. Classify Insulin and Oral Hypoglycaemic Drugs.
Write in brief about DPP-4 inhibitors.
Short Answer Questions 4 X 5 = 20
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Q2.
a. Discuss the mechanism of action, therapeutic uses
and unwanted effect of phenytoin.
b. A 60-year-old lady is suffering from rheumatoid
arthritis and has been prescribed prednisolone.
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Answer the following:i. What is the mechanism of action of glucocorticoids?
ii. Name two glucocorticoids which have no
mineralocorticoid activity.
iii. Enumerate the adverse effects that you expect in this
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patient.c. Classify macrolide antibiotics. Describe briefly its
mechanism of action and mention four uses.
d. Classify H, anti-histamines. Enumerates their
therapeutics use.
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e. Classify Anti-Psychotic Drugs. Write in brief aboutadverse drug reactions of Anti-Psychotic Drugs.
f. Classify Penicillins. Describe their therapeutic uses
and adverse effects.
Very Short Answer Questions 1 X 10 = 10
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Q3.a. Explain why - Ethyl alcohol is used in methyl alcohol
poisoning.
b. Explain why- Bromocriptine is effective even after
Levodopa fails in Parkinsonism.
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c. Describe the pharmacological basis of usingLignocaine as local anaesthetics.
d. Mention two drugs for prevention of AIDS in the new
born.
e. Multidrug therapy of paucibacillary leprosy..
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f. Enumerate four chelating agents.g. Enumerate four viral vaccines.
h. Drug therapy of Migraine.
i. Describe the pharmacological basis of using Lithium
in Mania.
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j. Explain why -Levodopa is not given with Vitamin B6.***