Download VNSGU MBBS Second Year 2024 February-March 2106000102010102 Pathology Paper II Question Paper

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2106000102010102

Examination February – March 2024

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SECOND MBBS

PATHOLOGY (PAPER - II ) - LEVEL 1

[Time: Three Hours]

[Max. Marks:100 ]

Instructions:

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1. Fill up strictly the following details on your answer book
   1. Name of the Examination : SECOND MBBS
   2. Name of the Subject : PATHOLOGY ( PAPER - II ) - LEVEL 1 (OMR)
   3. Subject Code No : 2106000102010102
2. Sketch neat and labelled diagram wherever necessary.

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3. Figures to the right indicate full marks of the question.
4. All questions are compulsory.
5. No negative marks

Seat No:

Student's Signature

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SECTION-I

Q.1 Multiple choice questions (MCQs). 20*1=20

(Instruction: Encircle the correct answer)

1. Erythropoietin is produced by
   1. Liver
   2. Bone marrow

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   3. Lungs
   4. Kidney
2. Which is NOT SEEN in Megaloblastic anaemia?
   1. Hyper segmented neutrophil
   2. Evidence of dyserythropoesis

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   3. MCV < 80
   4. Giant metamyelocytes
3. Howell Jolly bodies in red cells seen in:
   1. Hereditary Spherocytosis
   2. Post Splenectomy

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   3. Lead Poisoning
   4. Iron deficiency anemia
4. Thepathognomic abnormality in ß-thalassaemia minor is:
   1. marked rise in HbA2
   2. marked rise in HbF

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   3. marked unconjugated hyperbilirubinaemia
   4. marked anaemia
5. Small warty vegetations along the lines of closure of Valves on mitral and aortic valves are obserevedin :
   1. Infective endocarditis
   2. Rheumatic fever

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   3. Libman -Sach's endocarditis
   4. Non-Bacterial thrombotic endocarditis
6. The commonest vessel involved in Myocardial Infarction:
   1. Right Coronary artery
   2. Left Circumflex artery

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   3. Left Anterior Descending artery
   4. Posterior Descending artery
7. Which of the following is associated with the development of bronchogenic carcinoma and mesothelioma?
   1. Silicosis
   2. Siderosilicosis

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   3. Asbestosis
   4. Anthracosis
8. Patients are designated as pink puffers in:
   1. Chronic Bronchitis
   2. Emphysema

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   3. Bronchiectasis
   4. Pneumoconiosis
9. Essential diagnostic criteria for nephrotic syndrome in adults is :
   1. Anasarca with orbital puffiness
   2. 24hrs urinary excretion of protein 3.5 gm or greater

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   3. Hypoalbuminemia
   4. A constellation of hypertension, hyperlipedemia and lipiduria
10. Typical "Grain Leather" appearance of kidney is seen in :
    1. Benign nephrosclerosis
    2. Nephrocalcinosis

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    3. Malignant nephrosclerosis
    4. Necrotising Papillitis
11. Toxic Megacolon is complication of:
    1. Crohn's Disease
    2. Necrotising Enterocolitis

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    3. Ulcerative Colitis
    4. Pseudomembranous Colitis
12. The most common site for hydatid cyst is
    1. Liver
    2. Spleen

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    3. Lungs
    4. Brain
13. The most common mechanism in pathogenesis of chronic pyelonephritis is
    1. Ascending infection
    2. Obstructive nephropathy

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    3. Reflux nephropathy
    4. Haematogenous infection
14. Cirrhosis in Wilson's disease is related to:
    1. Zinc
    2. Mercury

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    3. Copper
    4. Iron
15. Ovarian tumour arising from Stromal cells is :
    1. Dysgerminoma
    2. Brenner tumour

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    3. Granulosa theca cell tumour
    4. Krukenberg Tumour
16. Giant cell tumour arises from:
    1. Diaphysis
    2. Articular cartilage

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    3. Metaphysis
    4. Epiphysis
17. Gout is characterised by deposition of crystals of
    1. Uric acid
    2. Pyrophosphate

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    3. Hydroxy apatite
    4. Urate
18. Mutation characteristic of polycythaemia vera
    1. JAK2
    2. p53

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    3. Bcr-abl
    4. RAS
19. Medullary carcinoma of thyroid arises from:
    1. C-cells of thyroid
    2. Follicular cells

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    3. Parathyroid cells
    4. Primitive pluripotent cell of thyroid
20. Which type of Nevus most commonly progresses to Malignant Melanoma:
    1. Blue cell Nevus
    2. Dysplastic Nevus

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    3. Spindle cell Nevus
    4. Compound Nevus

SECTION - II

Q.2 Case based Question (Compulsory to attempt ) 13

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1. A 50year male with history of chronic alcohol consumption presented with distended abdomen .ultrasound scan show reduced size of liver.
   1. What is the probablediagnosis? 1
   2. Describe the pathogenesis of this condition 5
   3. Describe gross and microscopic findings. 4
   4. Enumerate three Complications of the condition. 3

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Q.3 Long Essay Questions: (Attempt any 3 out of 4) 9*3=27

1. Describe the Clinical features, pathogenesis and Lab findings in ? Thalassemia Major. 3+3+3
2. Describe etiopathogenesis, gross and microscopy & complications of ulcerative colitis. 4+3+2
3. Describe the Pathogenesis and stages of lobar pneumonia. 3+6
4. Describe etiopathogenesis of Hypertension vascular Disease. Write About Benign and Malignant Nephrosclerosis. 4+5

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SECTION – III

Q.4 (Attempt any 8 out of 10) (5 marks each ) 40

1. Describe clinical findings, inheritance in von Willebrand disease.
2. Classify germ cell Tumour. Describe Morphological features of Seminoma.
3. Describe Major and Minor criteria to diagnose Rheumatic Heart disease.

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4. Write the staging Classification of Hodgkin Lymphoma.
5. Giant cell Tumour of Bone
6. Atherosclerosis
7. Squamous cell carcinoma
8. Lab findings in Megaloblastic Anaemia

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9. Describe morphologic features of Fibroadenoma.
10. Describe the Pathogenesis and morphology Of Bronchiectasis.

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