Q.P. Code: 201001
Reg. No.: .........................
Second Professional MBBS Degree Supplementary Examinations
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February 2021
Pharmacology - Paper I
Time: 2 Hours
Max Marks: 40
- Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers
- Indicate the question number correctly for the answer in the margin space
- Answer all parts of a single question together. Leave sufficient space between answers
- Draw table/diagrams/flow charts wherever necessary
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Essays: (2x6=12)
- Classify anticholinergic drugs. Describe the pharmacological actions, therapeutic uses and contraindications of atropine.
- A 50 years old male patient came to hospital with a complaint of breathlessness, Orthopnoea and swelling of both feet since 10 days. He is a known ischemic heart disease patient, using aspirin only and not taking the other drugs as prescribed. His heart rate is 128/mt and his blood pressure is 160/100 mm of Hg. Echocardiogram shows dilated cardiac chambers.
- Classify drugs used in congestive heart failure
- Explain the mechanism and pharmacological action of digoxin
- Describe the adverse effects of beta blockers
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Short Notes: (5x3=15)
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- Pharmacogenetics
- Prazosin
- Diazepam
- Selective serotonin reuptake inhibitors
- Prophylaxis of migraine
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Write the Pharmacological basis for the use of: (3x1=3)
- Adrenaline in anaphylactic shock
- Fomepizole in methanol poisoning
- Tramadol as analgesic
Write two uses and two adverse effects of the following drugs: (3x1=3)
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- Lignocaine
- Carbamazepine
- Isosorbidedinitrate
Choose the appropriate drug and Justify: (2x1=2)
- Naloxone/Methadone in morphine addiction
- Frusemide/Hydrochlorothiazide as antihypertensive
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Name the following (Two examples for each): (5x1=5)
- Oral direct factor Xa inhibitors
- Mast cell stabilizers
- Antitussives
- Recombinant tissue plasminogen activators
- Aldosterone antagonists
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