Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2018 May (Master of Pharmacy) 1st Year 9349 Advanced Pharmacology And Toxicology Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - MAY-2018
[Time: 3 Hours]
[Max. Marks: 100]
Advanced Pharmacology and Toxicology
(Revised Scheme 4)
Q.P. CODE: 9349
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.
LONG ESSAY (Answer any TEN)
10 X 10 = 100 Marks
1.
Explain the role of various chemical mediators in inflammation.
2.
Explain in vivo mutagenicity tests in rodents.
3.
Discuss intracellular signal transduction mediated through IP3-DAG pathway.
4.
Describe the adrenergic transmission. Explain the biosynthesis, metabolism and physiological
role of adrenaline.
5.
Explain the pathophysiology and pharmacotherapy of depression. Discuss the mechanism of
action of sertraline.
6.
Classify anti-hypertensive agents with examples. Explain the mechanism of diuretics and
calcium channel blockers in treatment of hypertension.
7.
Write a brief description of endocrine functions of pancreas. Explain the mechanism of action of
oral antidiabetic drugs.
8.
What is osteoporosis? Explain the pathophysiology and pharmacotherapy of post-menopausal
osteoporosis.
9.
Discuss the pathophysiology and management of urinary tract infections.
10.
Classify anti HIV agents. Explain the mechanism of action of Zidovudine and discuss the
pharmacotherapy of HIV infection.
11.
What is Schizophrenia? Write its pathophysiology and pharmacotherapy.
12.
Write the pharmacotherapy in Peptic ulcer and write the mechanism of each class of Anti ulcer
drugs.
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