Download KUHS MBBS First Year 2012 March 1501 Biochemistry Paper I Question Paper

Reg. no.:

First Professional MBBS Degree Supplementary Examinations, March 2012

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BIOCHEMISTRY- PAPER I

Time: 3 Hours

Total Marks: 50

Essay

• Answer all questions

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• Draw diagrams wherever necessary

1. Define Kreb's cycle. Describe the reactions of Kreb's cycle. Add a note on its energetics and significance. (1+6+1+2=10)
2. Discuss the following:
   1. Describe the reactions of ketogenesis and its regulation. (2x5=10)
3. Define secondary structure of proteins and mention its types. Describe about α-helix. (5x3=15)

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4. Write short notes on:
   1. Define mucopolysaccharides and give two examples.
   2. Describe the functions of mitochondria.
   3. Define phospholipids and how are they classified.
   4. Define feed back inhibition and give two examples.
   5. What are uncouplers. Give two examples. (5x2=10)

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5. Answer briefly:
   1. Define epimers and give two examples.
   2. Define optimum pH and give one example.
   3. What are isomerases?
   4. What is Cori's disease and mention the enzyme defect in it?

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   5. Mention the four functions of albumin. (5x1=5)
6. Give precise answers:
   1. Name the defective enzyme in galactosemia.
   2. Name two polyunsaturated fatty acids.
   3. Define active site of an enzyme.

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   4. Name two conditions causing increased urea level.
   5. Name the enzyme defect in Maple syrup urine disease.

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