Download KNRUHS MBBS Final Year 2025 February MB2019131 General Medicine Paper I Previous Question Paper

KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES

TELANGANA STATE, WARANGAL – 506 002

FINAL MBBS PART-II DEGREE EXAMINATIONS: FEBRUARY, 2025

GENERAL MEDICINE

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Paper - I

Time: 3 Hours Max Marks: 100

Note: Answer all questions

Give Diagrammatic representation wherever necessary

Multiple Choice Questions: 10 × 1 = 10

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1. Wolf-Chaikoff effect is due to
   1. lodine deficiency
   2. Excessive iodine
   3. lodine metabolism defect
   4. Tpo enzyme deficiency

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2. Triad of Renal Cell Carcinoma includes all except
   1. Haematuria
   2. Abdominal pain
   3. Abdominal mass
   4. Fever

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3. The following an Auto Recessive condition (AR)
   1. Peutz-Jeghers syndrome
   2. Tuberous sclerosis
   3. Neurofibromatosis
   4. Ataxia telangiectasia

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4. Treatment of choice in ulcerative colitis
   1. 5-amino salicylic acid
   2. Azathioprine
   3. Metronidazole
   4. Salicylates

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5. Alpha 1 antitrypsin in stool is indicative of
   1. Protein losing enteropathy
   2. Chronic pancreatitis
   3. Acute pancreatitis
   4. Whipple disease

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6. Gene therapy is used for
   1. Cystic fibrosis
   2. Spinocerebellar ataxia
   3. Thalassemia
   4. All of the above

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7. Obesity is not a feature of
   1. Hypothyroidism
   2. Adrenal insufficiency
   3. Hypogonadism
   4. Cushing's syndrome

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8. Which of the following drug is not a part of "triple therapy" immunosuppression for post renal transplantation patient
   1. Cyclosporin
   2. Azathioprine
   3. Tacrolimus
   4. Prednisolone

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9. Most common histological variant of Renal Cell Carcinoma
   1. Clear cell type
   2. Chromophobe type
   3. Papillary type
   4. Tubular type

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10. Renal artery stenosis is associated with
    1. High renin hypertension
    2. Normal renin hypertension
    3. Low renin hypertension
    4. Fibrinoid necrosis of vessels

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Essay / Long Answer Questions: 2 × 15 = 30

11. Hyperthyroidism – aetiology, clinical features, diagnosis, and management.
12. Draw diagram of nephron and write about aetiology, diagnosis and management of Acute Pyelonephritis.

Short Answer Questions: 7 x 6 = 42

13. A 72-year-old man presented with complaints of fatigability and chronic lower back pain; laboratory findings are as follows: Hb – 9 g%, serum calcium – 11.8 g/dl, bone marrow biopsy showed 15% clonal plasma cells. What is the most likely diagnosis and write clinical features management of the same.

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14. Irritable bowel syndrome – clinical features, diagnosis, and management.
15. List the causes of hematemesis and describe the management of acute variceal bleeding.
16. Blood transfusion therapy – indications, complications, precautions to be observed during transfusion.
17. Clinical features, and management of anaphylaxis.
18. Definition, types and how to approach a case of Fever of Unknown Origin (FUO).

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19. What are the care options to be communicated with terminally ill patient and family members.

Very Short Answer Questions: 6 × 3 = 18

20. Meig's syndrome.
21. GERD.
22. Agranulocytosis – causes.

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23. Anti-snake venom therapy – indications.
24. Non-shivering thermogenesis.
25. Types of consent. Add brief note on informed consent.

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