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Download ABVMU MBBS 2nd Year Microbiology Paper II 2022 Question Paper

Download ABVMU (Atal Bihari Vajpayee Medical University) MBBS (A Bachelor of Medicine, Bachelor of Surgery) 2nd Year (Second Year) Microbiology Paper II 2022 Previous Question Paper

This post was last modified on 13 March 2023

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Paper II

Time Allowed: Three Hours

Maximum Marks- 100

Note: Attempt all questions in serial order. Answer Section-A and Section-B in separate answer books. All parts of a question should be answered together. Illustrate your answer with suitable diagram where required.

Figures in parenthesis indicate marks allotted to a question.

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Section-A

Q1. Write in detail the clinical picture, pathogenesis, diagnosis and management of tuberculosis (20)

Q2. Write briefly on: (4x5)

  1. Causes of Viral pneumonia
  2. Dengue virus
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  4. Covid vaccines
  5. Rabies

Q3. Multiple Choice Questions: (10x1)

  1. XDR tuberculosis is defined as
    1. Resistance to Rifampicin and Isoniazid
    2. MDR plus resistance to any fluroquinolones plus resistance to any injectable second line anti tubercular drug
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    4. Resistance to all second line anti tubercular drugs
    5. Resistance to any fluroquinolones and resistance to all injectable second line anti tubercular drugs
  2. Mutations in katG gene of Mycobacterium tuberculosis are responsible for resistance to
    1. Isoniazid
    2. Rifampicin
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    4. Pyrazinamide
    5. Streptomycin
  3. What would be the phenotype of cells infected with HIV-1 during primary stage of the infection?
    1. CD4/CXCR4
    2. CD8/CXCR4
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    4. CD4/CCR5
    5. CD8/CCR5
  4. The following viruses replicate in the nucleus
    1. Herpesviruses
    2. Poxviruses
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    4. Picornaviruses
    5. Paramyxovirues
  5. The following is not a "slow virus" disease
    1. Creutzfeldt-Jacob disease
    2. Subacute Sclerosing Panencephalitis (SSPE)
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    4. Herpes Simplex Encephalitis
    5. Progressive multifocal leukoencephalopathy (PML)
  6. Bacteriophages are readily counted by the process of:
    1. Immunoassay
    2. Plaque assays
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    4. Tissue culture
    5. Electron Microscopy
  7. Which of the following statement about Hepatitis C virus is FALSE?
    1. Is associated with hepatocellular carcinoma
    2. May respond to interferon therapy
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    4. Has one stable genotype only
    5. May cause chronic infection
  8. Which of the following statements is FALSE
    1. Dengue virus infection result from bites by Aedes mosquitoes
    2. Cases of dengue haemorrhagic fever usually result from reinfection by a different serotype of dengue virus
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    4. Pigs act as the reservoir for dengue virus
    5. Dengue antibodies cross react with Japanese encephalitis virus antibodies
  9. According to WHO, which of the following is a bad clinical practice in management of dengue cases?
    1. Assessment and follow-up of patients with non-severe dengue and careful instruction of warning signs to watch out for
    2. Administration of acetylsalicylic acid (aspirin) or ibuprofen
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    4. Clinical assessment of the haemodynamic status before and after each fluid bolus
    5. Giving intravenous fluid volume just sufficient to maintain effective circulation during the period of plasma leakage for severe dengue
  10. Which of the following viruses can cause a self-limiting acute febrile illness with rash in immune-competent children but has been associated with transient aplastic crises in persons with sickle cell disease?
    1. Measles
    2. Human Parvovirus B19
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    4. Rubella
    5. Herpes simplex

Section-B

Q1. Describe parasitic infections of immune-compromised host. Discuss in detail structure, life cycle, pathogenesis and diagnosis of any one of them. (20)

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Q2. Write short notes on: (4x5)

  1. Candidiasis
  2. Dimorphic fungi
  3. Mucormycosis
  4. Subcutaneous fungal infections
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Q3. Multiple Choice Questions: (10x1)

  1. In malaria, the form of plasmodia that is transmitted from mosquito to human is the
    1. Sporozoite
    2. Gametocyte
    3. Merozoite
    4. Hypnozoite
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  2. Trophozoites, Schizonts and gametocytes of all the malarial parasites are seen in peripheral blood smear EXCEPT
    1. Plasmodium vivax
    2. Plasmodium falciparum
    3. Plasmodium malariae
    4. Plasmodium ovale
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  3. Which of the following statements regarding Plasmodium falciparum is FALSE
    1. Causes more severe disease in pregnancy
    2. Is associated with recurrent relapses after initial treatment because of liver hypnozoites
    3. Is the only malarial parasite causing greater than 20% parasitaemia
    4. Infection may be associated with thrombocytopenia
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  4. Congenital Toxoplasmosis manifest as
    1. Microcephaly
    2. Micro-opthalmus
    3. Hepatosplenomegaly
    4. ALL of the above
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  5. Which is the smallest tape worm infecting man
    1. Taenia saginata
    2. Taenia solium
    3. Hymenolepis nana
    4. Diphyllobothrium latum
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  6. Superficial fungal infection of hair shaft is called
    1. Pityriasis
    2. Piedra
    3. Ring worm
    4. Thrush
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  7. Which of the following is NOT a predisposing factor for mucormycosis?
    1. Injection drug use
    2. Desferoxamine therapy
    3. Diabetic ketoacidosis
    4. Patients on isavuconazole
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  8. Each of the following statements concerning Candida albicans is correct EXCEPT
    1. C. albicans is a budding yeast that forms pseudohyphae when it invades tissue
    2. C. albicans causes thrush
    3. C. albicans is transmitted primarily by respiratory aerosol
    4. Impaired cell mediated immunity is an important predisposing factor to disease
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  9. Infection with dermatophyte is most often associated with
    1. Intravenous drug abuse
    2. Inhalation of the organism from contaminated bird feces
    3. Adherence of the organism to skin moist by perspiration
    4. Fecal-oral transmission
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  10. Fungal cells that reproduce by budding are seen in the infected tissues of patients with
    1. Candidiasis, cryptococcosis, and sporotrichosis
    2. Mycetoma, candidiasis and mucormycosis
    3. Tinea corporis, tinea unguium, and tinea versicolor
    4. Sporotrichosis, mycetoma and aspergillosis
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