F.Y. M.B.B.S.
E) GENETICS
i) Introduction ? Mendelism, Laws Genetic code
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Level 2: Evolution, Eugenics and Polygenic inheritance, Radiation andmutation , Sex chromatin, Population genetics
ii) Cytogenetics
Structure and function of chromosomes, Cell cycle, Cell divisions,
Spermatogenesis, Oogenesis
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iii) Molecular genetics (Normal)Gene, Genetic code, Structure and types of DNA, Structure of RNA
iv) Inheritance: Single gene inheritance, Multifactorial inheritance,
Polygenic inheritance, Mitochondrial inheritance, Pedigree charts with
symbols
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Genetic basis of variation
Mutation, Polymorphism, Multiple allelism
Level 2: Types, Factors influencing mutational load
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Developmental geneticschromosomes; Lyon's hypothesis; Hermaphroditism and
pseudohermaphroditism; teratogenesis
Gonadal dysgenesis, Adrenogenital syndrome Androgen insensitivity
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Level 3: Counselling
Pedigree charting
Chromosomal basis of disease: Numerical, Structural abnormalities
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Down's, Cri-du-chat, Turner's, Klinefelter'sLevel 2: Dermatographics
Level 3: Counselling
Prenatal diagnosis
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Maternal Serum Sampling; Fetal USG; Fetal Amniocentesis; FetalChorion Villus Sampling
Level 2: (cordocentesis); Foetoscopy
Level 3: Eugenics
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