PTU B.Tech 9th Semester Last 10 Years Previous Question Papers|| Punjab Technical University
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| Roll No. | Total No. of Questions : 08 | Total No. of Pages : 01 |
M.Tech (Bio Tech) EL-I (2018 Batch) (Sem.-1)
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PHARMACEUTICAL BIOTECHNOLOGY
| Subject Code : MTBT-108-18 | M.Code:75768 |
| Time: 3 Hrs. | Max. Marks : 60 |
INSTRUCTIONS TO CANDIDATES :
- Attempt any FIVE questions out of EIGHT questions.
- Each question carries TWELVE marks.
- (a) Discuss the various phases of Drug Discovery and Development Process. (08)
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(b) Define Rational Drug Design. What are the different strategies of Rational Drug Design? (02+02) - Discuss the process of the production of monoclonal antibodies and add a note on its merits when compared to other methods of antibody production. (12)
- Insulin is used for the management of Diabetes. How has recombinant DNA technology revolutionised the production of Human Insulin? Add a note on different types (native and engineered) Insulin being produced (08+04)
- Write Short notes on (any two- 600 words max.) (06×2=12)
a) Biosimilars--- Content provided by FirstRanker.com ---
b) Biomedical applications of protein drugs
c) High throughput Screening - Give an account of different routes of administration of Drugs, with relevant examples. (12)
- (a) Explain the role of USFDA in the process of Drug Approval. (08)
(b) What are therapeutic peptides? Give properties and routes of administration of therapeutic peptides. (01+03) - (a) Give brief account on the role of protein engineering in drug designing. (06)
(b) Why are protein therapeutics generally not active on oral administration? (06) - Discuss the major elimination pathways for protein drugs after administration. (12)
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NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
| 1 M-75768 | (S35)-1937 |
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