0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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Max Marks: 501. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any
TWO of the following
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a) Factors affecting enzyme activity(10)
(A. 60) (C.88)
b) What is acidosis? Describe metabolic
and respiratory acidosis. (A. 402) (C. 481)
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c) Electrophoresis serum proteins (A. 384)(C.724)
2. Write Short notes of (any
three)
a) Lipid peroxidation (A. 428) (C. 656) (9)
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b) Phospholipids (A. 108) (C.34)c) Enzyme Inhibitions (A. 63)(C.92)
d) Diasaccharides (A. 94)(C.18)
e) Acute intermittent porphyria (A. 328)
(C.212)
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3. Discuss Any TWOa) Blood buffer system (A. 398) (C.475)(6)
b) Homeostasis of body fluid (A. 411)
(C.469)
c) Plasma membrane transport (A. 15)
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(C.651)Section 2
4. Write Short notes on (any
two)
a) Gluconeogenesis (A. 135) (C.258) (10)
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b) Biochemical change in starvation (A.122) (C.383)
c) Fatty acid oxidations (A. 194) (C.287)
5. Write Short notes on (any
two)
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a) IgG (A. 649) (C.188)(9)
b) Chemi-osmotic theory of oxidative
phosphorylation (A.318) (C.228) Lead
poisoning (A. 532) (C.666)
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c) Oncogene (A. 664) (C.687)d) Inhibitors of electron transport chain (A.
320) (C.232)
6. Give your comments with
justification of Any SIX:
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a) Fructose is not a stereo isomer of(6)
glucose.
b) Enzyme works by reducing activation
energy of a reaction.
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c) Phospholipids are amphipathic in nature.d) Mucopolysaccharides retain water in
extra cellular space.
e) Bicarbonate buffer is the front line
defense for acid base balance in blood.
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f) Carbon dioxide in atmosphere isresponsible for "green house effect".
g) Unsaturated fatty acid in the cell
membrane is responsible for fluidity of
membrane.
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h) Carbon mono oxide in exhaust gas ofvehicle is harmful.