0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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Max Marks: 50Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1.Give an account of any TWO of
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the following(10)
a) Liver function tests and its clinical
significance (A. 361) (C.453)
b) Disturbances of acid-base balance
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with laboratory findings (A. 401)(C.479)
c) Competitive inhibition and its
therapeutic importance (A. 63) (C.92)
2.Write Short notes of (any three)
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(9)a) Mutarotation (A. 90) (C.14)
b) Phospholipids (A. 108) (C.34)
c) Porphyrias (A. 328) (C.212)
d) Iso enzymes (A. 69) (C. 109)
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e) Similarities and differencesbetween starch and glycogen (A. 96)
(C.20,21)
3.Discuss Any TWO
(6)
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a) Bicarbonate buffer system in the
blood and significance of Henderson-
Hasselbalch equation (A. 398)
(C.475)
b) ELISA (A. 437) (C.729)
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c) Creatinine clearance test (A. 374)(C.461)
Section 2
4.Write Short notes on (any two)
(10)
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a) Hexose monophosphate shuntand its significance (A. 144) (C.270)
b) Ketone bodies generation and
utilization (A. 205) (C.294)
c) Glycogen metabolism and its
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hormonal regulation (A. 140) (C183)5.Write Short notes on (any two)
a) Detoxification by conjugation
(9)
mechanisms (A. 525) (C.640)
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b) Components of electron transportchain and sites of ATP synthesis (A.
315) (C.226)
c) Tumor markers (A. 666) (C.691)
d) Functions of plasma proteins (A.
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385) (C.183)e) Malate-Aspartate shuttle (A. 136)
(C.234)
6.Give your comments with
justification of Any SIX:
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(6)a) Lead toxicity causes anemia.
b) Cataract is seen in children
suffering from galactosemia.
c) Ketone bodies are not utilized by
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liver.d) Defective synthesis of VLDL may
result in fatty liver.
e) Glucose 6 phosphate
dehydrogenase causes anemia.
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f) B-oxidation of odd chain fatty acidgives propionic acid.
g) Streptokinase is used in treating
acute myocardial infarction.
h) Glucagon as hyperglycemic
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hormoneDocument Outline
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