First Year MBBS Examination
I MBBS Biochemistry Paper 1
Date: 11-01-2012 Time: 3 hours Max
Marks: 50
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1. Answer to the points.2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
4. Draw diagrams wherever necessary.
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5. Write legibly.Section 1
1. Give an account of any TWO of
the following
(10)
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a) Isoenzymes and their clinicalimportance (A. 69, 78) (C.112)
b) Role of kidney in acid base
regulation (A. 399) (C.477)
c) Principle and significance of Van
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Den Bergh's reaction (A. 359)(C.455)
2. Write Short notes of (any three)
(9)
a) Essential fatty acids (A. 241)
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(C.509)b) Glycosides (A. 93) (C.17)
c) Allosteric enzymes (A. 66) (C.95)
d) Fluid mosaic model of membrane
(A. 13) (C.650)
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e) Radioisotopes of medical
importance (A. 683) (C.717)
3. Discuss Any TWO
(6)
a) Active transport and passive
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transport (A. 15) (C.651)b) Radioimmunoassay (A. 436)
(C.729)
c) Acute intermittent porphyria (A.
328) (C.212)
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Section 24. Write Short notes on (any two)
(10)
a) Gluconeogenesis (A. 135)
(C.258)
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b) Beta oxidation of fatty acids (A.194) (C.287)
c) Oxidation of pyruvate (A. 135)
(C.252)
5. Write Short notes on (any two)
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(9)a) Regulation of Citric acid cycle.
(A. 308) (C.257)
b) Immunoglobulins (A. 649) (C.186)
c) Oxidative phosphorylation (A. 318)
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(C.228)d) Antioxidants (A. 429) (C.658)
e) Cori cycle (A. 134) (C. 261)
6. Give your comments with
justification of Any SIX
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(6)a) Enzymes are proteins
b) Sucrose is also called as invert
sugar.
c) Bile salts are required for digestion
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of lipids.d) Cyanide causes instantaneous
death.
e) Acetyl CoA is a common metabolic
intermediate
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f) Phytanic acid accumulates in alphaoxidation defect.
g) Lysophospholipid is formed during
snake bite.
h) People with glucose 6-phosphate
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dehydrogenase deficiency areresistant against malaria.