0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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Max Marks: 50Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
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following(10)
a) Role of kidney in acid-base balance (A.
399) (C.477)
b) Clinical importance of enzymes. (A. 78)
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(C.105)
c) Thyroid function tests and its clinical
importance. (A. 637) (C.465)
2. Write Short notes of (any three)
(9)
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a) Reducing reactions of carbohydrates (A.91) (C.16)
b) Prostaglandins (A. 243) (C.644)
c) Heme breakdown (A. 330) (C. 214)
d) Oligosaccharides (A. 88) (C.10)
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e) Isozymes (A. 69)3. Discuss Any TWO
(6)
a) Mechanism of enzyme catalysis (A. 56)
b) Spectroscopy (A. 438) (C.727)
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c) Inhibitors of electron transport chain (A.320) (C. 232)
Section 2
4. Write Short notes on (any two)
(10)
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a) Gluconeogenesis and its regulation (A.135) (C.258)
b) Metabolic importance of cholesterol (A.
215) (C.313)
c) Galactose catabolism and related
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disorders (A. 182) (C.276)5. Write Short notes on (any two)
(9)
a) Redox potential and its importance in
ATP synthesis. (A. 312) (C.224)
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b) Tumor markers (A. 666) (C.691)c) Immunoglobulins. (A. 649) (C.186)
d) Lipoproteins. (A. 217) (C. 317)
e) Fatty liver. (A. 204) (C.322)
6. Give your comments with justification
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of Any SIX(6)
a) Increased LDL cholesterol is bad for
health.
b) Liver Glycogen breakdown increases
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blood glucose level.c) Krebs cycle is common oxidative process.
d) Phospholipids are polar lipids.
e) Hyaluronic acid is lubricant in nature.
f) HMP shunt is necessary for RBC
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g) Isozymes are important tool for diagnosisfor diseases.
h) Methylation of drugs in body makes them
less toxic.