224 E 656
First Year MBBS Examination
I MBBS Physiology Paper 2
Time: 3 hours
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Max Marks: 100Instructions: 1. Answer to the points. 2.
Use separate answer books for each
section. 3. Draw diagrams wherever
necessary.
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Section 11. Write the following structured long
questions (Any 1 out of 2)
1X 10 = 10 Marks
a. Enumerate the
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various parts of Basal ganglia.Describe the connections & functions
of the basal ganglia. Enumerate the
clinical features of Parkinsonism.
(2+3+2+3= 10)
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(10)b. With the help of diagram explain the
dorsal column medial lemniscal
pathway. Write in brief about the
spinal & supraspinal analgesia
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system. (7+3 = 10)2. Write the following case-based
scenario/applied short notes (Any 2 out
of 3)
2X 6 =12 Marks
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a. A young boy suffers from spinalmuscular atrophy which is
characterized by loss of motor
neurons in the ventral horn of the
spinal cord. What shall be the
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features of muscles affected in suchpatients (2) What are the features of
paralysis in this patient (2) What are
the features of superficial & deep
reflexes in such patients (2)
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(12)b. A 45-year-old lady came to hospital
with complains of weight gain despite
poor appetite, constipation, cold
intolerance, tiredness, hoarse voice,
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poor memory & inability toconcentrate. On examination her
extremities were cool & skin was dry
& coarse. She had bradycardia,
diastolic hypertension, edematous
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hands & feet, diffuse alopecia.a)What could be the most probable
diagnosis. Q) b) What investigations
would you like to conduct? (2) c)
What is the physiological basis of
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clinical features of this disease (3)c. Describe the various stages of
spermatogenesis. Add a note on
semen analysis. (4+2 = 6)
3. Write short notes on the following (Any
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3 out of 4)3X6 = 18 Marks
a. Enterohepatic circulation of bile salts
(18)
b. Menstrual cycle
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c. Exocrine pancreasd. Physiological changes in pregnancy
4. Answer in only 2-3 sentences. (Any 5
out of 6)
5 X2=10 Marks
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a. Post prandial alkaline tide(10)
b. Role of Jendrassik maneuver
c. Mechanism of action of intrauterine
contraceptive devices
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d. Traveling wave theory of sound wavese. Mechanism of analgesia produced by
acupuncture & counterirritant creams.
f. Why is dimorphic anemia usually
produced in patients after total
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gastrectomySection 2
1. Write the following structured long
question (Any 1 out of 2)
1X 10 = 10 Marks
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a. Enumerate thelayers of adrenal cortex and
hormones secreted by each of them.
Describe the actions of
Glucocorticoids. Add a note on
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Cushing syndrome. (2+5+3 = 10)(10)
b. Explain the mechanism of action of
Insulin. Explain the pathophysiology
of Diabetes Mellitus. Differentiate
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between Type I & Type II DiabetesMellitus. (3+4+3 = 10)
2. Write short notes on (Any 2 out of 3)
2X 6=12 Marks
a. Mechanism of smooth
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muscle contraction-
(12)
b. Neuromuscular junction disorders &
blockers
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c. Wallerian degeneration andregeneration of nerve
3. Write short notes on (Any 3 out of 4)
3X 6= 18 Marks
a. Color blindness
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(18)b. Visual reflexes
c. Neurotransmitters of autonomic
nervous system
d. Tuning fork tests of hearing
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4. Answer in only 2-3 sentences (Any 5 outof 6)
5X2 = 10 Marks
a. Cause of Trousseau's sign in patients
after thyroid surgery f
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(10)b. Why insulin is given with glucose in
treatment of hyperkalemia
c. Sarcotubular system of skeletal
muscle;
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d. Physiology of rigor mortis
e. How anterior pituitary tumor causes
visual field defect & what is the type
of defect.
f. Why after prolonged steroid therapy
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the medicine should not be stoppedsuddenly.