0824 E202
First Year MBBS Examination
I MBBS Physiology Paper 1
Time: 3 hours
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Max Marks: 100Instructions: 1. Answer to the points. 2. Use
separate answer books for each section. 3. Draw
diagrams wherever necessary.
Section 1
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1. Write the following structured long question(Any 1 out of 2) 1x10=10 Marks (10)
a. Define cardiac cycle and give its duration.
Describe the various atrial and ventricular
events occurring during cardiac cycle along
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with pressure and volume changes. (2 + 8)b. With the help of a neat labelled diagram
describe the Pace maker potential in heart.
Explain the efforts of Sympathetic and
Parasympathetic stimulation on Pace maker
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potential. (4 + 6)2. Case based scenario/ Applied short notes (any 2
out of 3) 2x6=12 marks (12)
a. A 55-year-old male came to OPD with
complaint of pain in chest radiating to left arm
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when he climbed the stairs to his fourth-flooroffice. There was no pain at rest. His ECG was
recorded. His condition was diagnosed as
Angina Pectoris. a) Draw and label a normal
ECG as recorded in limb lead 1. (2) b) What
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as the cause of pain in angina pectoris? Howcan it be relieved? (1) c) Explain why the pain
was radiating to the left arm? (1) d)Whatare
the other investigations required to diagnose
such a case? (1) e0Explain the role of daily
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administration of low dose of aspirin in such acase. (1)
b. A 10-year-old boy was brought to casualty with
complaints of puffiness of face, edema of feet
and decreased urinary output since last 3 days.
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There was past history of repeated sore throat.On examination: Pulse - 90/minute, B.P
150/110 mm Hg Urine examination: Albumin
++ Blood Urea and serum creatinine were
increased. He was diagnosed as acute
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glomerulonephritis. A. What is the relationshipbetween sore throat and acute
glomerulonephritis (2) B. Why is there
puffiness of face and edema of feet? (1) C Why
albumin was present in his urine? D. Explain
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the Hypertension in this case. (2)c. A 65-year-old man came to medicine OPD
with complaint of cough with expectoration
since last one week. He was having
progressive breathlessness since one month.
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He was smoking 10 cigarettes per day sincelast 25 years. One examination chest was
barrel shaped. Respiratory rate: 20/minute
Lung function test showed: 1) FRC -3.5.Liters
2) FVC -4 Liters 3) FEV:-65% 4) FEV,75% 5)
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Lung compliance - 0.4 Licm of water Identifythe abnormal Lung function Tests and give
their normal values. (1) Calculate the specific
lung compliance from above report and give
the significance of specific compliance. (2)
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Explain how emphysema is developed inchronic smokers. (2) Why was his chest barrel
shaped? (1)
3. Write shorts notes on the following, (Any 3 out of
4) 3 X 6 = 18 Marks (18)
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a. Functions of Neutrophils,b. Anemias
c. Rh blood group system.
d. Active Transport mechanisms across cell
membrane.
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4. Answer in only 2-3 sentences, (Any 6 out of 6) 5X 2 = 10 Marks (10)
a. Positive feedback mechanisms.
b. Function of Thrombin.
c. Facilitated Diffusion.
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d. BY Function of Lymphocytes.e. Heart Sounds.
f. Ejection Fraction.
Section 2
1. Write the following structured long questions.
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(Any 1 out of 2) 1 X 10 = 10 Marks. (10)a. Describe the chemical regulation of
respiration. Explain in detail Hypoxic
Hypoxia. (6+4)
b. Describe the transport of oxygen from lungs to
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tissues. Draw a neat labelled diagram ofoxygen Haemoglobin dissociation curve.
Explain the conditions that shift this curve to
left or right (5+3+2)
2. Write short notes on (Any 2 out of 3) 2 X 6 = 12
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Marks. (12)a. Cardio - respiratory changes during exercise.
b. Role of Kidney in maintaining Acid base
balance.
c. Mechanisms involved in blood clotting.
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3. Write short notes on the following. (Any 3 out of4) 3 X 6 = 18 Marks (18)
a. Glomerular filtration rate.
b. Mechanisms of concentration of Urine
c. Renal handling of glucose.
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d. Doctor - Patient relationship4. Answer in only 2 - 3 sentences. (Any 5 out of 6) 5
X 2 = 10 Marks (10)
a. Obesity
b. Mechanisms of Heat gain.
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c. What is Bohr Effect and Haldane Effect.
d. What is Oxygen Debt.
e. what is Scuba Diving.
f. Why a shipwreck victim drinking sea water
cannot survive.
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