1123E354
First Year MBBS Examination
I MBBS Physiology Paper 2
Time: 3 hours Max Marks: 100
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Instructions: 1. Answer to the points. 2. Useseparate answer books for each section. 3.
Draw diagrams wherever necessary.
Section 1
1.Write the following structured long
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question (any 1 out of 2) (10)a. Enumerate the ascending tracts of the spinal
cord. Trace the pathway of Pain. Discuss the
types of pain, referred pain, role of dorsal
horn of spinal cord on modulation of pain.
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(2+2+6)b. What is the role of cerebellum in motor
activity?What are the symptoms of
cerebellar disease and what is the
pathophysiology of the symptoms? (4+6)
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2.Write the following case - based scenario /applied short notes (any 2 out of 3) (12)
a. A 55 yrs. old non-diabetic female had
rheumatoid arthritis and was treated with
teroids for four months, after which she was
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advised to taper the medicine slowly alongtwo weeks before stopping it completely.
Along with steroids she was given calcium
tablets daily and her blood sugar was tested
every month. During her course of treatment,
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she developed swelling on her face and backof neck, purplish stria along the body, hair
loss from scalp and hirsutism.a) Give
physiological basis of the symptoms that she
developed. (2) b) Why were the steroids
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tapered slowly and not stopped abruptly atthe end of four months? (2) c) Why was she
given calcium along with steroids and why
was her blood sugar tested every month? (2)
b. An 85 year old male suffers from memory
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loss of recent events. The long term memoryis intact and so is his skills and reflexive
memory. What do you think is the most
likely diagnosis? What is the physiological
basis of this disease?
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c. Describe the various indicators of ovulation.3.Write short notes (any 3 out of 4) (18)
a. HCI secretion in the stomach
b. Gastrointestinal hormones
c. Hormonal changes in menstrual cycle
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d. Sertolii cells4.Answer in only 2-3 sentence (any 5 out of
6) (10)
a. Why salivation increases by mere thought or
sight of food?
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b. Oxytocin is present in the blood all the timebut it causes uterine contractions only at the
time of delivery. Why?
c. Babies born to elderly mothers are at a
higher risk of developing Down'syndrome
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d. Explain why, fetus is a 'transplant' in themother, yet it is well tolerated.
e. Why people sometimes experience pain in
their limb which has been amputated and is
no longer present
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f. What is Babinski's reflex?Section 2
5.Write the following structured long
question (any 1 out of 2) (10)
a. Name the hormones regulating the blood
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glucose levels. What is the mechanism ofaction of insulin? What is the difference
between type1 and type 2 diabetes? (2+2+6)
b. Name the hormones secreted from Pituitary
gland? How is the secretion of these
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hormones regulated? (3+7)6.Write short notes (any 2 out of 3) (12)
a. Action potential of cardiac muscle
b. Excitation Contraction coupling of skeletal
muscle
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c. Classification of nerves7.Write short notes (any 3 out of 4) (18)
a. Organ of Corti
b. Fight or Flight response
c. Color Vision
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d. Nicotinic and muscarinic receptors in ANS8.Answer in only 2-3 sentence (any 5 out of
6) (10)
a. What happens to a person who suddenly
enters cinema hall from the bright light?
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Why?b. Why there is polyphagoa in diabete patients?
c. What is the difference betweenconduction
velocity in myelinated and non myelinated
nerve fibers and why?
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d. What is the difference between rigor mortisand contracture?
e. Why tea doesn't taste sweet if it is taken just
after having sweet dish
f. Why vagotomy is done in severe cases of
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peptic ulcer?