Date: 19-11-2024
1124E 348
First Year MBBS Examination
I MBBS Physiology Paper 2
Time: 3 hours Max Marks: 100

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Instructions: 1. Answer to the points. 2. Use
separate answer books for each section. 3.
Draw diagrams wherever necessary.
Section 1
1. Write the following structured long question.

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(Any 1 out of 2) 1x10=10 Marks (10)
a) Describe muscle spindle and analyse their
function as a part of feedback system that
control muscle length. (5x2=10)
b) What is hemiplegia? List the clinical feature

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of this condition. Write the differences
between UMN lesion and LMN lesion.
(3+3+4=10)

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2. Case based scenario. (Any 2 out of 3)
2x6=12 Marks (12)

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a) A patient aged 70 year brought to hospital
with history of difficulty in walking, stoops
forwards while walking and abnormal rhythmic
movement in hands at rest. 1. What is the
probable diagnosis? (2) 2. What are other

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clinical features of the disease? (2) 3. Explain
the physiological basis for the clinical
features. (2)
b) A 50 year old lady came to OPD with
complaints of swelling in the neck and

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observed little protrusion of eyes. She also
complained of tremors in hand. 1. What is
probable diagnosis? (2) 2. How to confirm it?
(2) 3. What is the physiological basis of her
signs and symptoms? (2)

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c) A 46 year old female visited gynaecologist
with complaints of increased and irregular
duration between her menstrual cycles. She

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also complains of increased irritability, fatigue,
mood swings. 1. What is the condition called?

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(1) 2. What changes occur in this condition?
(3) 3. Risk factors of which diseases
increased after this condition? (2)
3. Write short notes on: (Any 3 out of 4)
3x6=18 Marks (18)

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a) Dumping syndrome
b) Indicators of ovulation
c) Exocrine function of pancreas
d) Malabsorption syndrome
4. Answer in only 2-3 sentences. (Any 5 out of

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6) 5x2=10 Marks (10)
a) Why lactation leads to temporary infertility?
b) Why only one sperm can penetrate the
egg?
c) Law of projection.

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d) Why boys are taller than girls?
e) Why blood becomes alkaline following
meals?
f) Why pancreas is not autodigested?
Section 2

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5. Write the following structured long question.
(Any 1 out of 2) 1x10=10 Marks (10)
a) What are the hormones secreted from the
posterior pituitary? Discuss their actions.
What is SIADH? (2+5+3=10)

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b) A 40 year old male presented with
symptoms of weakness, fatigue, weight loss
and anorexia. Examination revealed increased
pigmentation of skin and mucous membranes.
Blood investigation revealed Plasma Cortisol

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low, ACTH levels were high i. What is the
cause of this condition? (2) 2. What is the
physiological basis seen in this case? (5) 3.
Write the mechanism of action of hormones

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involved in this condition. (3)

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6. Write short notes on: (Any 2 out of 3)
2x6=12 Marks (12)
a) Excitation-contraction coupling
b) Latch bridge mechanism
c) Classification of nerve fibres

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7. Write short notes on: (Any 3 out of 4)
3x6=18 Marks (18)
a) Accommodation reflex
b) Organ of corti
c) Olfactory pathway

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d) Myasthenia gravis
8. Answer in only 2-3 sentences. (Any 5 out of
6) 5x2=10 Marks (10)
a) Why do we feel hotter on humid day?

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b) Why there is yellowish tinge in

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hypothyroidism?
c) Why visceral pain is poorly localised?
d) Why there is drooping of eyelids in Horner
syndrome?
e) Hypocalcemia is seldom a cause of

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bleeding disorder.
f) Why showing light in right eye leads to
papillary constriction in left eye?

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Document Outline

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