First Year MBBS Examination
I MBBS Physiology Paper 1
Date: 05-01-2022
Time: 3 hours
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Max Marks: 100Instructions: 1. Answer to the points. 2. Use
separate answer books for each section. 3.
Draw diagrams wherever necessary.
Section 1
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1. Write the following structured long question(any 1 out of 2) (10)
a. Describe factors affecting Heart rate.
Describe mechanism of control of heart rate.
b. What is mean arterial blood pressure?
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Describe long term regulation of arterialblood pressure.
2. Write the following case - based scenario /
applied short notes (any 2 out of 3) (12)
a. 30 year male, labourer complaint of
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progressive weakness, pallor, tinglingnumbness in the extremities, redness over
the tongue. He is strict vegetarian. On
examination shows pallor, inflammation of
the tongue, No other CNS abnormality.
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Blood Report - HB , RBC, WBC, MCV,MCH, MCHC - Normal, PBS - Shows
megaloblast.a) What is diagnosis and cause
of the condition? b) Which other
hematological investigation is required to
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diagnose the condition? c) What are thelikely complications of this disease?
b. 30 year female known diabetes mellitus
delivered a baby in 27th week of gestation.
On examination of a baby shows - rapid
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shallow breathing Difficulty in respirationintercostals retraction seen on inspection on
auscultation of chest harsh tubular sound
heard progressive cyanosis a) What is
diagnosis of the baby and cause of it.
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b)What is the treatment for it? c) How toprevent this condition?
c. Describe Dynamic lung volumes and
capacities.
3. Write short notes (any 3 out of 4) (18)
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a. Describe facilitated diffusion.b. Describe Na+ - K+ pump and its function.
c. Differentiate active and passive immunity.
d. Describe apoptosis. Give its significance.
4. Answer in only 2-3 sentence (any 5 out of 6)
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(10)a. Factors affecting cell membrane
permeability.
b. Function of eosinophil.
c. Sites of haemopoiesis.
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d. Give any two causes of increase plasmaosmolality.
e. SA node act as a pace maker in mammalian
heart.
f. Role of atrial systole in end diastolic volume.
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Section 21. Write the following structured long question
(any 1 out of 2) (10)
a. Describe role of chemoreceptors in the
regulation.
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b. Describe transport of oxygen in the arterialblood. Add a note on oxygen dissociation
curve.
2. Write short notes (any 2 out of 3) (12)
a. Mechanism of development of fever and its
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benefits.b. Respiratory and cardio vascular adaptation
to the exercise.
c. Positive feedback mechanism and its
significance.
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3. Write short notes (any 3 out of 4) (18)a. Juxtaglomerular apparatus.
b. Angiotensin II.
c. Function of proximal tubule.
d. Duties and responsibility of the patient.
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4. Answer in only 2-3 sentence (any 5 out of 6)(10)
a. Frequency of micturation seen in the patient
of diabetes mellitus.
b. Enumerate mechanisms in the body to
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maintain PH produced by acid base disorder.c. During the phase of swallowing apnea
develops.
d. 10% of drowning cases death occurs without
any water in the lung.
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e. Cyanosis is a common occurrence inhypoxic hypoxi
f. Acclimatized subject can also suffer from
mountain sickness.