Date: 05-04-2022
0422 E309
First Year MBBS Examination
I MBBS Physiology Paper 1
Time: 3 hours
Instructions: 1. Answer to the points. 2. Use
separate answer books for each section. 3. Draw
diagrams wherever necessary.
Section 1
1 out of 2) (10)
a. Enumerate the properties of cardiac muscle?
Discuss in detail the four basic properties of
cardiac muscle.
regulation of arterial blood pressure.
2. Write the following case - based scenario /
applied short notes (any 2 out of 3) (12)
a. A 28-year-old man is brought to the emergency
They complained that they found him in the
basement of their home next to a furnace,
where he was trying to stay warm on a cold
winter day. He appeared to be confused,
headache. He had no past h/(history of) major
medical complaints. On examination, the
patient was lethargic and confused but his lips
appeared a bright pink. A urine drug screen
carboxyhemoglobin level was elevated. The
patient was diagnosed with carbon monoxide
poisoning and was admitted to the hospital for
further treatment. a)Define hypoxia and
b)What is the mechanism by which carbon
monoxide causes hypoxia? c) Discuss
indications of oxygen therapy.
b. A 4-year-old boy is brought to the pediatrician
bleeding around the knees and elbows. The
parents noted that the child bleeds very easily
when the skin is scratched. Family history is
significant for the presence of hemophilia in
case of hemophili Laboratory findings:-
Complete blood cell (CBC): Hemoglobin: 10.9
g/dL (normal: 14-14 g/dL), Hematocrit: 32%
(normal: 40%-54%), Platelets: 200,000/mm3
thromboplastin time): 42 sec (normal: 24-35
sec), Bleeding time: 6 min (Normal: 2-8 min),
Factor VIII: C level: 5% (normal: 25%-100%).
a) Describe in short, the different types of
increased clotting time? c) Discuss in short,
the functions of platelets.
c. Explain in short micturition reflex. Add a note
on cystometrogram?
a. Metabolism of hemoglobin.
b. Resting membrane potential.
c. Active transport.
d. Actions of immunoglobulins (Antibodies).
a. Enumerate the different types of heart sounds.
b. Functions of the cell membrane.
c. Cause of sickle-cell anemi
d. Define homeostasis.
grouping?
f. P-wave in ECG.
Section 2
5. Write the following structured long question (any
a. Discuss the neural regulation of respiration.
b. Explain in detail the mechanics of ventilation.
6. Write short notes (any 2 out of 3) (12)
a. Explain the mechanism of fever.
c. Cardiovascular adaptation to exercise.
7. Write short notes (any 3 out of 4) (18)
a. Countercurrent mechanism in kidneys.
b. Describe the role of a physician in the health
c. Difference between cortical and juxta-
glomerular nephrons.
d. Renin-angiotensin system.
8. Answer in only 2-3 sentence (any 5 out of 6) (10)
b. Define oxygen debt.
c. What is caisson disease?
d. Define heat-stroke.
e. What do you mean by renal threshold?
0422 E309
First Year MBBS Examination
I MBBS Physiology Paper 1
Time: 3 hours
--- Content provided by FirstRanker.com ---
Max Marks: 100Instructions: 1. Answer to the points. 2. Use
separate answer books for each section. 3. Draw
diagrams wherever necessary.
Section 1
--- Content provided by FirstRanker.com ---
1. Write the following structured long question (any1 out of 2) (10)
a. Enumerate the properties of cardiac muscle?
Discuss in detail the four basic properties of
cardiac muscle.
--- Content provided by FirstRanker.com ---
b. Define blood pressure. Discuss the short-termregulation of arterial blood pressure.
2. Write the following case - based scenario /
applied short notes (any 2 out of 3) (12)
a. A 28-year-old man is brought to the emergency
--- Content provided by FirstRanker.com ---
wing of a hospital by his family members.They complained that they found him in the
basement of their home next to a furnace,
where he was trying to stay warm on a cold
winter day. He appeared to be confused,
--- Content provided by FirstRanker.com ---
nauseated, short of breath and complained of aheadache. He had no past h/(history of) major
medical complaints. On examination, the
patient was lethargic and confused but his lips
appeared a bright pink. A urine drug screen
--- Content provided by FirstRanker.com ---
was obtained and was negative. His serumcarboxyhemoglobin level was elevated. The
patient was diagnosed with carbon monoxide
poisoning and was admitted to the hospital for
further treatment. a)Define hypoxia and
--- Content provided by FirstRanker.com ---
explain in short the different types of hypoxia?b)What is the mechanism by which carbon
monoxide causes hypoxia? c) Discuss
indications of oxygen therapy.
b. A 4-year-old boy is brought to the pediatrician
--- Content provided by FirstRanker.com ---
by his parents, who have noted excessivebleeding around the knees and elbows. The
parents noted that the child bleeds very easily
when the skin is scratched. Family history is
significant for the presence of hemophilia in
--- Content provided by FirstRanker.com ---
the mother's family. He is diagnosed with acase of hemophili Laboratory findings:-
Complete blood cell (CBC): Hemoglobin: 10.9
g/dL (normal: 14-14 g/dL), Hematocrit: 32%
(normal: 40%-54%), Platelets: 200,000/mm3
--- Content provided by FirstRanker.com ---
(normal: 11-15 sec), APTT (activated partialthromboplastin time): 42 sec (normal: 24-35
sec), Bleeding time: 6 min (Normal: 2-8 min),
Factor VIII: C level: 5% (normal: 25%-100%).
a) Describe in short, the different types of
--- Content provided by FirstRanker.com ---
hemophilia? b)What are the causes ofincreased clotting time? c) Discuss in short,
the functions of platelets.
c. Explain in short micturition reflex. Add a note
on cystometrogram?
--- Content provided by FirstRanker.com ---
3. Write short notes (any 3 out of 4) (18)a. Metabolism of hemoglobin.
b. Resting membrane potential.
c. Active transport.
d. Actions of immunoglobulins (Antibodies).
--- Content provided by FirstRanker.com ---
4. Answer in only 2-3 sentence (any 5 out of 6) (10)a. Enumerate the different types of heart sounds.
b. Functions of the cell membrane.
c. Cause of sickle-cell anemi
d. Define homeostasis.
--- Content provided by FirstRanker.com ---
e. What are different blood groups in ABO-bloodgrouping?
f. P-wave in ECG.
Section 2
5. Write the following structured long question (any
--- Content provided by FirstRanker.com ---
1 out of 2) (10)a. Discuss the neural regulation of respiration.
b. Explain in detail the mechanics of ventilation.
6. Write short notes (any 2 out of 3) (12)
a. Explain the mechanism of fever.
--- Content provided by FirstRanker.com ---
b. Obesity.c. Cardiovascular adaptation to exercise.
7. Write short notes (any 3 out of 4) (18)
a. Countercurrent mechanism in kidneys.
b. Describe the role of a physician in the health
--- Content provided by FirstRanker.com ---
care system.c. Difference between cortical and juxta-
glomerular nephrons.
d. Renin-angiotensin system.
8. Answer in only 2-3 sentence (any 5 out of 6) (10)
--- Content provided by FirstRanker.com ---
a. Define cyanosis.b. Define oxygen debt.
c. What is caisson disease?
d. Define heat-stroke.
e. What do you mean by renal threshold?
--- Content provided by FirstRanker.com ---
f. Define renal clearance of a substance.