0423 E001
Second Year MBBS Examination
II MBBS Pathology Paper 2
Time: 3 hours
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Max Marks: 100Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Structured long Question (Any 1 out of
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2)(10)
a) Define Emphysema. Discuss its
etiology and pathological features.
b) What are the types of renal lesions in
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Diabetes Mellitus. Describe theirmorphological features with labeled
diagram.
2. Case based scenario/Applied short
notes (Any 2 out of 3)
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(12)a) 40 years male with complaints of
weakness, lethargy, night sweats and
increase thirst. His blood investigations:
Hb 11 gm%, TLC 7000/cumm platelets
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2.5 lac/cumm, Fasting blood sugar level150gm/dL Randam blood sugar
200mg/dL, serum bilirubin 0.5mg
/dl.I)What is your likely diagnosis. II)
What is the etiopathogenesis and
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complications of the disease process.b) 30 yrs male presented with fever,
abdominal pain and vomiting since one
week. His blood investigations: Hb 10
gm%, TLC 17000/cumm.platelets 2.0
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lac/cumm,serum bilirubin 25mg%,SGPTand SGOT were normal but serum
Alkaline Phosphatase was highly raised.I)
What is your likely diagnosis.II) Describe
the causes and types of the disease.
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c) 20 years young male presented with apainful hard mass in the upper end of
tibia. He had difficulty in walking. X ray
revealed a huge lytic lesion at the
metaphysis of tibia.I)What is your
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probable diagnosis. Give twocharacteristic radiological signs for the
diagnosis.II) Describe clinical and
pathological features of malignant bone
tumors in young adults.
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3. Write short notes(Any 3 out of 4)(18)
a) Basal cell Carcinoma
b) causes of hemoptysis
c) Types of chronic gastritis
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d) Paraneoplastic syndrome4. Answer in short (Any 5 out of 6)
(10)
a) Name three morphological features of
Pleomorphic Adenoma
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b) Write Four differentiating pointsbetween peptic and deuodenal ulcers
c) What is Seminoma
d) Write three characteristic microscopic
features of Osteoclastoma
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e) Define Sago spleenf) Types of gallstones
Section 2
5. Structured long Question(Any 1 out of
2)
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(10)a) Describe the physical cytological and
biochemical investigations of urine and
explain their role in the diagnosis of
various diseases. (2+2+3+3)
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b) What is Graves Disease. Describethyroid function tests in detail. (5+5)
6. Case based scenario/Applied short
notes (Any 2 out of 3)
(12)
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a) On autopsy of 50 years old male, liverwas enlarged, nodular and fibrotic. He had
history of chronic alcohol intake with
complaints of nausea, vomiting and
abdominal pain.I)What is your likely
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diagnosis II) Describe the pathologicaltypes and biochemical profile to approach
the diagnosis.
b) What is myocardial Infarction?
Describe role of cardiac markers in
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diagnosis of MI.c) What is Liquid Based cytology?
Describe various screening tests for the
early diagnosis of cervical cancer.
7. Write short notes(Any 3 out of 4)
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(18)a) Etiological factors of Breast cancer
b) Squamous cell Carcinoma
c) causes of honeycomb iung
d) CSF findings in Tubercular meningitis
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8. Answer in short (Any 5 out of 6)(10)
a) Define Bence Jones proteins
b) What is CAPLANS Syndrome
c) Two characteristic findings of
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Rhinosclerodermad) Enumerate causes of nephrotic
Syndrome
e) Write histological components of
Mature cystic teratoma
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f) Define Aphthous ulcers