Date: 04-07-2013
0713 E032
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
following
a) What is Artemesinin combination
therapy (ACT)? Explain the rationale for
combining the drugs in ACT to treat malaria.
State any 2 ACT regimens available in India.
(A. 833, B. 780)
b) Insulin analogues. (A. 264, B. 882)
c) Direct thrombin inhibitors. (A. 620, 476)
2. Write Short notes of (any three)
(12)
parenteral iron therapy (A. 604, B. 494)
b) Drugs for hepatic amoebiasis (A. 843, B.
788)
c) Drugs for psoriasis (A. 891, B. 1013)
872)
3. Discuss Any Three
(12)
a) Mechanism of action and adverse
reaction of oral contraceptives (A. 323, B.
955)
b) Explain the pharmacological basis for use
of dietary fibers as laxatives. State the
indication for their use. (A. 672, B. 607)
administration for oxytocin. (A. 329, .
630)
d) Mechanism of action and therapeutic uses
of fluoroquinolones. (A. 710, 711, B. 647)
three sentences; (any six)
(6)
a) Why trastuzumab is used in
combination with chemotherapy for patients
b) Why rifabutin is preferred in anti-TB
regimen for HIV positive patients taking
protease inhibitors? (A. 778, B. 755)
c) Daily folic acid is recommended for all
B. 507)
d) Why sildenafil should not be prescribed
to patient taking nitrates in any form? (A.
542, . 972)
should be given between 27 and 36 weeks of
pregnancy. State the rationale for this
recommendation.
f) Why praziquantel is preferred over
solium infection?(A.855,8.813)
g) What is 'red man syndrome? How can it
be prevented?(A. 757, B. 669)
h) Which vitamin K preparation should not
deficiency? Why? (A. 616,B. 487)
0713 E032
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
--- Content provided by FirstRanker.com ---
Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
--- Content provided by FirstRanker.com ---
4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any TWO of the
following
--- Content provided by FirstRanker.com ---
(10)a) What is Artemesinin combination
therapy (ACT)? Explain the rationale for
combining the drugs in ACT to treat malaria.
State any 2 ACT regimens available in India.
--- Content provided by FirstRanker.com ---
(A. 833, B. 780)
b) Insulin analogues. (A. 264, B. 882)
c) Direct thrombin inhibitors. (A. 620, 476)
2. Write Short notes of (any three)
(12)
--- Content provided by FirstRanker.com ---
a) Indications and adverse reactionsparenteral iron therapy (A. 604, B. 494)
b) Drugs for hepatic amoebiasis (A. 843, B.
788)
c) Drugs for psoriasis (A. 891, B. 1013)
--- Content provided by FirstRanker.com ---
d) Drugs for thyrotoxic crisis (A. 256, .872)
3. Discuss Any Three
(12)
a) Mechanism of action and adverse
--- Content provided by FirstRanker.com ---
reaction of oral contraceptives (A. 323, B.
955)
b) Explain the pharmacological basis for use
of dietary fibers as laxatives. State the
indication for their use. (A. 672, B. 607)
--- Content provided by FirstRanker.com ---
c) Mechanism of action, routes ofadministration for oxytocin. (A. 329, .
630)
d) Mechanism of action and therapeutic uses
of fluoroquinolones. (A. 710, 711, B. 647)
--- Content provided by FirstRanker.com ---
4. Write Answer to the point in two orthree sentences; (any six)
(6)
a) Why trastuzumab is used in
combination with chemotherapy for patients
--- Content provided by FirstRanker.com ---
with breast cancer? (A.871,8.829)b) Why rifabutin is preferred in anti-TB
regimen for HIV positive patients taking
protease inhibitors? (A. 778, B. 755)
c) Daily folic acid is recommended for all
--- Content provided by FirstRanker.com ---
women in reproductive age, why? (A. 610,B. 507)
d) Why sildenafil should not be prescribed
to patient taking nitrates in any form? (A.
542, . 972)
--- Content provided by FirstRanker.com ---
e) It is recommended that Tdap vaccineshould be given between 27 and 36 weeks of
pregnancy. State the rationale for this
recommendation.
f) Why praziquantel is preferred over
--- Content provided by FirstRanker.com ---
niclosamide in the treatment of Taeniasolium infection?(A.855,8.813)
g) What is 'red man syndrome? How can it
be prevented?(A. 757, B. 669)
h) Which vitamin K preparation should not
--- Content provided by FirstRanker.com ---
be used in neonates with vitamin Kdeficiency? Why? (A. 616,B. 487)