0716 E015
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours Max Marks: 40
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Instructions:1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Write briefly (any two)
(10)
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a) Classify drugs used in the treatmentof dyslipidemia. Describe the
mechanism of action, therapeutic uses
and adverse effects of atorvastatin.
(A.635, 637)
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b) Classify local anesthetics. Describemechanism of action, therapeutic uses
and adverse effects of lignocaine. (A.
363, B. 241)
c) Classify ACE inhibitors. Describe
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mechanism of action, therapeutic usesand adverse effects of enalapril. (A.
501, B. 422)
2. Write briefly (any three)
(12)
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a) Preanesthetic medication (A. 118,386, . 105)
b) Compare and contrast atenolol and
metoprolol(A. 145, 563, B. 272)
c) Drug treatment of
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organophosphorous poisoning(A. 110,. 289)
d) Pharmacological factors affecting
bioavailability. (A. 16, . 11,12)
3. Write briefly (any three)
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(12)a) Leukotriene antagonists(A. 228, .
360)
b) Compare and contrast ibuprofen
and etoricoxib (A.206)
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c) Sodium valproate(A. 417, B. 131)d) Mivacurium (A. 354)
4. Answer in one or two
sentences (any six):
(6)
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a) Pharmacological basis for the useof levodopa and carbidopa in
parkinsonism
b) Pharmacological basis for the use
of aspirin and clopidogrel in ischemic
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heart diseasec) Pharmacological basis for the use
of ipratromium bromide in COPD
patients
d) Pharmacological basis for the use
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of furosemide and spironolactone inpatients with ascites and edema (A.
559, 579)
e) Pharmacological basis for the use
of pilocarpine in acute congestive
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glaucoma. (A.155, B. 1028)f) Pharmacological basis for the use of
tamsulocin in benign hypertrophy of
prostate
g) Pharmacological basis for the use
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of zolpidem in sleep onset insomniah) Pharmacological basis for the use
of nitrates and calcium channel
blockers in angina patients