0718 E169
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Write briefly (any two)
(10)
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a) Classify antiepileptic drugs.Mechanism of action and
pharmacological action of phenytoin.
Therapeutic uses and adverse effects of
phenytoin. (. 417, . 131)
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b) Classify antihypertensive drugs. Writethe mechanism of action and
pharmacological action of captopril.
Therapeutic uses and adverse effects of
captopril. (A. 501, . 422)
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c) Classify NSAIDS. Write the mechanismof action and pharmacological action of
aspirin. Therapeutic uses and adverse
effects of aspirin.
2. Write briefly (any three)
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(12)a) Treatment of organophosphorous
poisoning (A. 110, . 289)
b) Indications and contra indications of
B-blockers (A. 145, B. 276, 277)
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c) Therapeutic uses of prostaglandinanalogues (A. 189, . 343)
d) Biotransformation reaction
3. Write briefly (any three)
(12)
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a) Phramacotherapy of glaucoma (A. 151,. 1028)
b) Pharmacotherapy of bronchial asthma
c) Potassium sparing diuretics
d) Digoxin (A. 519, . 452)
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4. Answer in one or two sentences(any six):
(6)
a) Pharmacological basis for the use of
paracetamol in fever
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b) Pharmacological basis for the use ofusing morphine in left ventricular failure
c) Pharmacological basis for the use of
sumatriptan in migraine.
d) Pharmacological basis for the use of
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nitrates in anginae) Pharmacological basis for the use of
dopamine in cardiogenic shock
f) Pharmacological basis for the use of
terlipressin in acute bleeding oesophageal
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varicesg) Pharmacological basis for the use of
calcium disodium edetate in lead
poisoning
h) Pharmacological basis for the use of
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amantadine in Parkinsonism's disease