0718 E188
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
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Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Write briefly (any two)
a) Classify drugs used in peptic
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(10)ulcer. Discuss the mechanism of
action uses and adverse effects of
proton pump inhibitors(A. 657, B. 624)
b) Classify macrolide antibiotics. Write
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the mechanism of action &Antibacterial spectrum of
Erythromycin. Therapeutic uses and
adverse effects of Erythromycin
c) Classify anti amoebic drugs. Write
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the mechanism of action and antiprotozoal actions Of Metronidazole.
Therapeutic uses and adverse effects
of Metronidazole.
2. Write briefly (any three)
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a) Thiazolidinediones(12)
b) Mechanism of action and side effect
of aminoglycoside(A. 745, B. 675)
c) Mechanism of action and uses of
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antiplatelet drugsd) Antipseudomonal penicillins (A.724)
3. Write briefly (any three)
a) Pharmacotherapy of
(12)
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osteoporosisb) Pharmacotherapy of plasmodium
falciparum resistant malaria
c) Pharmacotherapy of MDR
tubercuoisis
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d) Methotrexate4. Answer in one or two
sentences (any six):
a) Pharmacological basis for the
(6)
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use of pyridoxine with isoniazidb) Pharmacological basis for the use
of folinic acid with methotrexate
c) Pharmacological basis for the use
of mesna with cyclophosphamide
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d) Pharmacological basis for the useof ergometrine in postpartum
haemorrhage
e) Pharmacological basis for the use
of erythropoietin in anemia of chronic
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renal failuref) Pharmacological basis for the use of
tazobactam with piperacillin
g) Pharmacological basis for the use
of tamoxifen in breast cancer
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h) Pharmacological basis for the useof corticosteroid as
immunosuppressant