Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
Max Marks: 40
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Date: 13-01-20101. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any TWO of the
following
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(10)a) Discuss drug treatment of
hypertension (A. 568, . 425)
b) Discuss pharmacotherapy of
Parkinsonism (A. 425, B. 225)
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c) Discuss pharmacotherapy ofmyasthenia gravis (A. 109, B. 287)
2. Write Short notes of (any three)
a) What is meant by first pass
(12)
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metabolism? Give four attributes ofdrugs with high first pass hepatic
metabolism. Give two examples. (A. 27,
B. 14)
b) Enumerate therapeutic uses and
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adverse effects of Bblockers(A.147,8.269)
c) Write short note on
'methylxanthines'. (A. 224, B. 183)
d) Give four examples of uterine
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stimulants. Enlist their uses. (A. 329, .627)
3. Discuss Any Three
(12)
a) Define with example "teratogenecity
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and latrogenecity". (A.89, B.1101)b) Enumerate uses of anticholinegic
drugs (A. 118, . 295)
c) Mention indications and adverse
effects of furosemide (A. 579, . 556)
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d) Classify calcium channel blockersgiving example. Enlist their different
uses. (A. 546, . 398)
4. Write Answer to the point in two or
three sentences: (any six)
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(6)a) Give two examples of
pharmacokinetic type of drug
interactions. (A. 929, B. 2)
b) Give two examples of enzyme
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inducers. (A. 26, . 18)c) Why should morphine be avoided in
patients with head injury? (A. 474, .
152)
d) Why adrenaline is used with local
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anaesthetic? (. 363, . 238)e) Mention two advantages of
benzodiazepines over barbiturates as
hypnotic. (A. 401, 113)
f) Give two indications of therapeutic
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drug monitoring. (A. 34, B. 24)g) Why biliary colic is treated with
atropine-morphine combinations?
h) Why ace inhibitors should not be
combined with potassium sparing
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diuretics? (A. 502, B. 558)