GTU BE/B.Tech 2019 Winter Question Papers || Gujarat Technological University
- Brief about the conversion of phenylalanine to tyrosine. Describe in detail about phenylketonurias.
- Write in detail about ammonia production, transport and disposal. Add a note on disorders of urea cycle.
- Write briefly the mechanisms by which the pH of the body fluids is regulated. Add a note on acid base disturbances with examples.
- Explain the biochemical basis of clinical features of porphyrias.
- Describe the pathways of methionine metabolism. Add a note on metabolic functions of methionine and cysteine.
- Describe the biosynthesis of purine nucleotide. Add a note on regulation.
- Describe the biosynthesis of purine nucleotide. Add a note on regulation.
- Name the compounds derived from glycine. Explain any two in detail.
- Describe in detail the mechanism of regulation of blood PH.
- Name liver function tests with diagnostic significance of each. Write in detail the biochemical tests of any three done in your laboratory.
- Describe the pathway for synthesis of urea from ammonia. What is normal blood urea level? Name the conditions in which blood urea level is increased and give the biochemical basis.
- Describe the steps of s-adenosyl methionine cycle. Explain the term transmethylation with five suitable examples.
- Describe the separation of Serum Proteins by paper electrophoresis. Draw the pattern of electrophoresis in i) Multiple Myeloma ii) Nephrotic Syndrome.
- How is blood pH regulated?
- Write in details about the initiation, elongation and termination of transcription. Give an account of post transcriptional processing.
- Write in detail about the absorption, transport, daily requirement and deficiency Manifestation of Iron.
- What is cloning? Mention the various types of cloning. Describe in detail the steps involved in recombinant DNA technology.
- Describe the role of plasma and renal buffers in maintaining acid base homeostasis.
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- Describe the metabolism of tyrosine. Name the inborn errors associated with this pathway.
- Enumerate the liver function tests and how Vanden Bergh test distinguishes different types of jaundice.
- With the help of a figure, describe the process by which DNA replication takes place in a cell.
- Name the Aromatic Aminoacids. Add a note on physiologically important derivatives of tyrosine.
- Explain Protein synthesis in detail. Add a note on drugs that inhibit protein synthesis
- Describe the catabolism of Heme in the body. Explain the different types of jaundice. How do you investigate a case of jaundice?
- What is the normal pH of blood. Describe the various mechanisms which maintain it? Mention the acid base disorders.
- List the parameters that are commonly used in clinical practice as indicators to assess the functions of the liver. Explain the basis of the use of these parameters in assessment of liver function. Briefly discuss medical conditions in which these parameters become abnormal.
- Describe the role of the kidney to maintain the pH of blood. What are the compensatory mechanisms the kidney will adopt to maintain pH in the presence of metabolic acidosis?
- What is the reference range for serum uric’acid? What is the source of uric acid in the body? What is its ultimate fate? Discuss causes of abnormalities in levels of serum uric acid.
- Describe recombinant DNA technology. Explain the different techniques with its application.
- Discuss in detail the replication of DNA. Mention the inhibitors of replication.
- Describe in detail the steps in protein synthesis. Add a note about Post translational modification and inhibitors of protein synthesis.
- Describe in detail the steps in protein synthesis. Add a note about Post translational modification and inhibitors of protein synthesis.
- What is a Buffer? Describe in detail about the Renal Regulation of Blood pH.
- Describe in detail about the formation and transport of ammonia in our body. Add a note on Urea cycle.
- Describe in detail about the Synthesis of Tyrosine and its metabolic endproducts.
- Name the important buffer systems in the body. Describe in detail the role of lungs and kidneys in maintenance of acid base balance.
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- What is polymerase chain reaction? Write a note on the steps involved in PCR and its applications.
- Phenyl ketonuria
- Formation of uric acid
- Porphyria
- Urea cycle
- ELISA
- Active Methionine
- Flame photometer
- Bilurubin formation & excretion
- Plasma proteins
- Replication
- Transamination reactions
- Renal regulation of pH
- Gout
- Mutation
- Differences between DNA and RNA
- Oncogenes
- Post translational modification
- Formation of creatine
- Alkaptonuria
- Southern blotting
- Disorders of Tyrosine metabolism
- Southern blot technique and its applications
- Write about post transcriptional processing Mention about post transcriptional inhibitors
- Describe about the various patterns of diseases in protein electrophoresis
- Structure of mRNA
- Liver function tests
- Laboratory investigations in different types of Jaundice
- Structure of DNA
- Purine Salvage pathway
- Metabolism of Methionine
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- What is Blotting technique? Write in detail about Southern blot technique
- Give a detailed account of how bilirubin is formed and excreted
- Transamination reaction and its significance
- Homocystinuria
- Essential amino acids
- Structure of tRNA
- Restriction endonucleases
- Post-translational modifications of proteins
- What is creatine clearance? Write the normal value of it
- Sources of ammonia in the body and its metabolism
- Functions of glycine in the body
- Heavy metal poisonings
- Disorders associated with potassium homeostasis
- Functions of nucleotides
- Denaturation of proteins
- Types of mutations
- Post-transcriptional modifications of RNA
- Restriction endonucleases and their uses
- Specialized products derived from tyrosine
- Principle and applications of electrophoresis
- Cell cycle
- Causes and clinical features of dehydration
- Consequences of hyperuricemia
- Structure of DNA
- Active form of methionine and its function
- Inhibitors of Protein Biosynthesis
- Porphyria
- LAC Operan
- Transcription & Post Transcriptional modification
- Cyclic AMP
- Detoxification by conjugation
- Renal Function Tests
- Tumor Markers
- Different mechanisms involved in hormone action
- Thyroid function Tests
- Recombinant DNA Technology
- Structure of DNA
- Post transcriptional modifications
- Functions of albumin
- Electrophoresis and its applications
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- Causes for respiratory acidosis
- Renal mechanism of maintaining Acid Base Balance
- Purine Salvage pathway
- Lac Operon concept
- Post translational modifications
- Electrophoresis
- Repair mechanism of DNA
- Salvage pathway of Purine synthesis
- Functions of Glucocorticoids
- Functions of albumin
- Precipitation reactions of Proteins
- Tubular function tests
- Role of Kidney in regulating the pH of blood
- Immunoglobulins
- Purine salvage pathway
- Explain the types and functions of immunoglobulins
- Phenylketonuria
- Fluorosis
- Serum protein electrophoresis
- Cell cycle
- Role of Parathormone in Calcium, Phosphate homeostasis
- Define Xenobiotics and add a note on the various detoxification reactions
- Mutation
- Secondary structure of protein
- Synthesis and mechanism of action of Nitric Oxide
- Homocystinurias
- Hyperuricemias
- Metabolic acidosis
- Phase Two detoxification
- Cyclic AMP
- Assessment of hypothyroidism
- Mutations
- Electrophoresis
- Antioxidants
- Genetic code
- Formation of Epinephrine
- Cytochrome
- Purine Salvage pathways
- Dehydration
- LAC operon
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- Orotic acidurias
- t RNA
- Phenyl ketoneuria
- Water toxicity
- Denaturation
- Reverse transcription
- Sphingolipidoses
- GOUT
- Metabolic acidosis
- Tumor markers
- Colorimeter
- Functions of adrenal cortical hormones
- Plasmid
- Functions of albumin
- Give an account of the formation of specialized products from glycine
- Explain the term transamination and its salient features
- Polymerase chain reaction and its applications
- Blotting techniques
- Gene therapy
- Werite an account of salvage pathway in purine nucleotide synthesis Add a note on Lesch — Nyhan syndrome
- Post translational modification
- What are porphyrias? Describe any three porphyrias in detail
- Give an account of water distribution and its balance in the body
- What are isotopes? What are its applications in biochemistry?
- Name the buffer systems of blood
- Sources of carbon and nitrogen in purine ring
- Wobble hypothesis
- Write the enzyme defect in (1) Lesch-Nyhan Syndrome (2) Orotic aciduria
- Okasaki fragments
- What are Xenobiotics
- Causes of Metabolic acidosis
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