Download MBBS 1st Year 2010 Feb 524056 Biochemistry II Question Paper

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[KW 505] FEBRUARY 2010 Sub. Code: 4056

FIRST M.B.B.S. DEGREE EXAMINATION

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Revised (Non-Semester) Regulations

PAPER VI – BIOCHEMISTRY - II

Q. P. Code : 524056 Maximum: 100 Marks

Time: Three hours

Answer ALL questions.

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Draw Suitable diagrams wherever necessary

I. Essay Questions : (2 x 15 = 30)

1. Discuss about nucleic acids under following headings:
   1. Types
   2. Functions
   3. Components

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   4. Char gaffs rule of DNA composition
   5. Different forms of DNA double helix and
   6. Differences between DNA and RNA.
2. Describe the steps of s-adenosyl methionine cycle. Explain the term transmethylation with five suitable examples.

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II. Write Short notes on : (10 x 5 = 50)

1. Give an account of the formation of specialized products from glycine.
2. Explain the term transamination and its salient features.
3. Polymerase chain reaction and its applications.
4. Blotting techniques.

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5. Gene therapy.
6. Write an account of salvage pathway in purine nucleotide synthesis. Add a note on Lesch-Nyhan syndrome.
7. Post translational modification.
8. What are porphyrias? Describe any three porphyrias in detail.
9. Give an account of water distribution and its balance in the body.

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10. What are isotopes? What are its applications in biochemistry?

III. Short Answer Questions : (10 x 2 = 20)

1. Phenyl keton uria.
2. Structure of t-RNA.
3. Okazaki pieces.

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4. Differences between CPSI and CPS II.
5. Metabolic role of magnesium.
6. Anion Gap.
7. Rotheras test.
8. Gout.

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9. Flurosis.
10. Vanden Berg test.

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