Download MBBS 1st Year 2012 Feb 524056 Biochemistry II Question Paper

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[LA 505]

FEBRUARY 2012

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Sub. Code: 4056

FIRST M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations

PAPER VI – BIOCHEMISTRY - II

Q. P. Code : 524056

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Time : 180 Minutes

Maximum: 50 Marks

Answer ALL questions in the same order.

I. Elaborate on :

1. Describe the metabolism of tyrosine. Name the inborn errors associated with this pathway. (10 x 1 = 10)

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2. Enumerate the liver function tests and how Vanden Bergh test distinguishes different types of jaundice. (5 x 1 = 5)

II. Write notes on: (10 x 2 = 20)

1. Post translational modifications.
2. Electrophoresis.
3. Repair mechanism of DNA.

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4. Salvage pathway of Purine synthesis.
5. Functions of Glucocorticoids.
6. Functions of albumin.
7. Precipitation reactions of Proteins.
8. Tubular function tests.

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9. Role of Kidney in regulating the pH of blood.
10. Immunoglobulins.

III. Short Answers on : (15 x 1 = 15)

1. Restriction Endonucleases.
2. Mutagens.

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3. Lesch Nyhan Syndrome.
4. Denaturation of Proteins.
5. Differences between DNA and RNA.
6. What are the enzymes required for DNA replication.
7. What is the principle of affinity Chromatography.

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8. What are the causes of respiratory acidosis.
9. Maple syrup urine disease.
10. Urea clearance.
11. Bence Jones Protein.
12. What are Oncogenes?

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13. Beer - Lambert's Laws.
14. What are the forces that stabilize secondary structure of Proteins.
15. Name the basic Amino Acids.

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