[LD 503]
NOVEMBER 2013
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Sub. Code: 4054
FIRST M.B.B.S. DEGREE EXAMINATION
PAPER IV – PHYSIOLOGY INCLUDING BIO-PHYSICS – II
Q. P. Code: 524054
Time: 180 Minutes
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Answer ALL questions
Maximum: 50 Marks
I. Elaborate on: (2 x 7.5 = 15)
- Define the term Blood pressure. Discuss the determinants and regulation of blood pressure.
- Trace the pathway for perception of pain. Discuss the descending pain modulatory pathways. Discuss the terms 'Gating of pain' and 'Referred pain'.
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II. Write notes on: (10 x 2.5 = 25)
- Ionic basis of the pace-maker potential.
- Windkessel effect of aorta.
- Illustrate with a diagram, the left ventricular volume and pressure changes during a cardiac cycle.
- Role of myelin sheath in conduction of nerve impulse.
- Functions of hypothalamus.
- Clinical features of cerebellar lesions
- Physiological roles of muscle spindle.
- Chemical regulation of respiration.
- Hamburger's chloride shift.
- Role of surfactant in pulmonary function
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III. Short Answers on: (10 x 1 = 10)
- List the calcium transporters on the sarcoplasmic reticular membrane in the ventricular Muscle.
- State Starling's law of the heart.
- What is the effect of 2,3 diphosphoglycerate on the oxygen-hemoglobin dissociation curve? Does it help in loading or unloading of oxygen?
- What are the types of hypoxia?
- Region of the cochlea which vibrates most for the highest sound frequency in the audible range.
- Visual field defect when the optic chiasma is cut in the centre.
- State the refractive error in astigmatism. How is it corrected?
- What is 'Blind spot'?
- Receptors for vestibular sensation.
- Name of tracts made up by second order neurons in the pathway for (a) fine touch (b) pain.
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