Download MBBS 2nd Year 2011 August 524063 General Pathology And Haematology Question Paper

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AUGUST 2011

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Sub. Code: 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations

Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY

Q. P. Code: 524063

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Time: Three hours

Maximum: 100 Marks

Answer ALL questions.

Draw Suitable diagrams wherever necessary

I. Essay Questions : (2 x 15 = 30)

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1. Define inflammation. Write in detail about the vascular and cellular changes in inflammation.
2. 40 yrs female c/o loss of weight, huge splenomegaly with peripheral blood white blood cell count of more than 1 lakh cells/cc
   1. What is the probable diagnosis?
   2. What are the characteristic peripheral smear findings?
   3. What is the course of the disease?
   4. What is the chromosomal abnormality involved?

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II. Write Short notes on : (10 x 5 = 50)

1. Classify pigments and write about Lipofuschin.
2. Write about outcomes of acute inflammation.
3. Growth factors.

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4. Hybridisation techniques to detect genomic alterations.
5. Antibody mediated hypersensitivity.
6. Molecular basis of cancer.
7. Immunology of Leprosy.
8. Primary myelofibrosis.

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9. Hemophilia A.
10. Peripheral smear and Bone marrow findings in Multiple Myeloma.

III. Short Answer questions : (10 x 2 = 20)

1. Define metaplasia and give two examples.
2. Antiphospholipid antibody syndrome.

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3. Mention four X linked recessive disorders.
4. Mention four special stains for Amyloid.
5. Lead and blood and marrow changes.
6. Four infections associated with AIDS.
7. Hamartoma.

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8. Prions.
9. Four Systemic effects of inflammation.
10. Hyper IGM syndrome.

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