AUGUST 2011
Sub. Code: 4065
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[KZ 544]
SECOND M.B.B.S. DEGREE EXAMINATION
Revised (Non-Semester) Regulations
Paper V - PHARMACOLOGY - I
Q. P. Code: 524065
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Time: Three hours
Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
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- (i) Enumerate the various sedative and hypnotic drugs.
(ii) Discuss the mechanism of action, uses and adverse effects of benzodiazepines.
(iii) Briefly discuss the management of acute barbiturate poisoning. - (i) Classify anticholinesterases
(ii) Discuss the mechanism of action and indications of reversible anti-cholinesterases--- Content provided by FirstRanker.com ---
(iii) Outline the management of acute organophosphorous poisoning.
II. Write Short notes on : (10 x 5 = 50)
- Mydriatics.
- Drugs used in prophylaxis of migraine.
- Receptor antagonism of drugs.
- Sublingual route of administration.
- Blood-Brain barrier.
- Therapeutic uses of loop diuretics.
- Parenteral iron therapy.
- Epsilon amino-caproic acid.
- Therapeutic uses of prostaglandin analogues.
- Uricosuric agents.
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III. Short Answer Questions (10 x 2 = 20)
- Mechanism of action of Disulfiram.
- What is potentiation of drug action? Mention two examples?
- What is Eutectic mixture? Mention its indications.
- Mention two uses, two advantages and two disadvantages of thiopentone sodium.
- What is first order kinetics?
- What is fixed dose combination? Give two examples
- Mention two selective Cox-2 inhibitors. What are the advantages?
- What are antitussives? Give two examples.
- Mention 2 thiazide diuretics. Mention two uses of thiazides.
- What is the mechanism of action and uses of Montelukast?
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