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[LB 542]
AUGUST 2012
Sub. Code: 4063
SECOND M.B.B.S. DEGREE EXAMINATION
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Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code: 524063
Time: 180 Minutes
Maximum: 40 Marks
Answer ALL questions.
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Draw Suitable diagrams wherever necessary
I. Elaborate on:
| Pages (Max.) | Time (Max.) | Marks (Max.) | |
|---|---|---|---|
| 1. Write in detail about carcinogenesis physical, chemical and biological and also molecular basis of Carcinogenesis. | 16 | 30 | 10 | 
| 2. Chronic myeloid leukemia – clinical features peripheral smear and bone marrow findings and clinical outcome. | 8 | 20 | 5 | 
II. Write notes on:
| 1. Air embolism. | 3 | 8 | 1.5 | 
| 2. Klinefelter syndrome. | 3 | 8 | 1.5 | 
| 3. Arthus reaction. | 3 | 8 | 1.5 | 
| 4. Morphology of Primary Tuberculosis. | 3 | 8 | 1.5 | 
| 5. Fracture healing. | 3 | 8 | 1.5 | 
| 6. Sickle cell disease. | 3 | 8 | 1.5 | 
| 7. Polycythemia vera. | 3 | 8 | 1.5 | 
| 8. Leukemoid reaction. | 3 | 8 | 1.5 | 
| 9. Christmas disease. | 3 | 8 | 1.5 | 
| 10. Fanconi's Anemia. | 3 | 8 | 1.5 | 
III. Short answers on:
| 1. Warthin-Finkeldey giant cells. | 2 | 5 | 1 | 
| 2. Factors downregulation apoptosis. | 2 | 5 | 1 | 
| 3. Gamma - Gandy bodies. | 2 | 5 | 1 | 
| 4. Virchow's triad. | 2 | 5 | 1 | 
| 5. Bernard - Soulier syndrome. | 2 | 5 | 1 | 
| 6. Sago spleen. | 2 | 5 | 1 | 
| 7. Two special stains for Amyloid. | 2 | 5 | 1 | 
| 8. Howell - Jolly bodies. | 2 | 5 | 1 | 
| 9. Tear drop cell. | 2 | 5 | 1 | 
| 10. MCV. | 2 | 5 | 1 | 
*******
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