[MBBS 0921]
SEPTEMBER 2021
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(FEBRUARY 2021 SESSION)
M.B.B.S. DEGREE EXAMINATION
SECOND YEAR
PAPER I - PHARMACOLOGY-I
Q.P. Code: 525061
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Time: Three hours Maximum: 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)
- A patient is brought to the emergency medicine dept with symptoms suggestive of Organo Phosphorous Compound (OPC) poisoning.
- What is the antidote for the above poisoning?
- Write in detail on receptor antagonism with suitable diagram.
- Write briefly on cholinergic crisis in Myasthenia Gravis.
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II. Write notes on: (6 x 4 = 24)
- Write Mechanism of action, therapeutic uses of newer antiepileptic drugs.
- Uses, adverse effects of Angiotensin Converting Enzyme (ACE) Inhibitors.
- Discuss the clinical significance of plasma protein binding with examples?
- Therapeutic uses of beta blockers and contraindications.
- Therapeutic uses of fibrinolytic drugs.
- Antitussives.
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III. Short answers on: (6 x 1 = 6)
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- Define pharmacogenetics, discuss with three examples.
- Rationale of Levodopa Carbidopa fixed drug combination.
- Enumerate direct oral anticoagulants.
- Define pharmacovigilance.
- Give three examples each for drugs with long and very short half life.
- Drugs used in treatment of alzheimers disease.
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