Download KUHS MBBS 1st Year 2022 May 115001 May 2022 Biochemistry Paper I Question Paper

Download KUHS (Kerala University of Health Sciences) A Bachelor of Medicine, Bachelor of Surgery (MBBS) 1st Year (First Year) 2022 May 115001 May 2022 Biochemistry Paper I Previous Question Paper || KUHS MBBS first year question papers

2019 Scheme

Q.P. Code: 115001

Reg. no.: .....................

First Professional MBBS Degree Supplementary (SAY) Examinations

May 2022

Biochemistry - Paper I

Time: 3 Hours

Total Marks: 100

Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers

? Indicate the question number correctly for the answer in the margin space

Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary

Long Essays

(2x15=30)

1. A 45-year-old man complaints of increased appetite, thirst, and frequent micturition. His

random blood sugar is 346 mg/dl

What is the diagnosis. What are the diagnostic criteria



Discuss the relevant investigations that can be done for further monitoring of the

patient

How is blood glucose regulated



What is the renal threshold for Glucose

(3+4+5+3)

2. Define Beta oxidation. Enumerate the steps and add a note on its regulation. Explain

the energetics for palmitic acid

(2+8+1+4)

Short essays

(5x8=40)

3. Enumerate the steps of TCA cycle. Add a note on malate shuttle

(6+2)

4. Describe the salient features of any two types of enzyme inhibition with suitable

examples

(2+2+2+2)

5. Define nitrogen balance. Add a note on the clinical conditions altering nitrogen balance























(2+6)

6. Discuss the catabolism of heme. Describe the causes and laboratory finding in

obstructive jaundice

(5+3)

7. What are the sources of vitamin A. Enumerate the biochemical role and deficiency

manifestations of vitamin A

(2+4+2)

Short answers

(5x4=20)

8. Define Peptide bonds. Enumerate two biochemically important peptides and their

significance.

(2+2)

9. Substrate level phosphorylation
10. Golgi complex
11. Discuss the formation of melanin and add a note on albinism
12. Describe the synthesis of any two compounds of biomedical importance synthesized

from glycine

Give Precise Answers

(10x1=10)

13. Why is sucrose a non reducing sugar
14. Enzyme defect in Alkaptonuria
15. Name two cardiac markers
16. Name two prostaglandins and mention their importance
17. Enzyme defect in Von-Gierke's disease
18. Give the normal reference range for ? Serum triglyceride ? Serum creatinine
19. Marker enzyme for mitochondria
20. Name two compounds formed from Tryptophan
21. Name the enzyme activity to assess the deficiency of vitamin B1
22. Name the rate limiting enzyme of heme synthesis.

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