Download KUHS (Kerala University of Health Sciences) A Bachelor of Medicine, Bachelor of Surgery (MBBS) 2nd Year (Second Year) 215001 January 2023 Microbiology Paper I Previous Question Paper || KUHS MBBS second year question papers
2019 Scheme
Q.P. Code: 215001
Reg. no.: .....................
Second Professional MBBS Degree Regular/Supplementary
Examinations January 2023
Microbiology - Paper I
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers ?
Indicate the question number correctly for the answer in the margin space
Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
Long Essays
(2x15=30)
1. A 30-year-old previously healthy woman presented to Medicine OPD with malaise, low-
grade fever, nausea, vomiting, aversion to food, mild itching since one month. Serum
showed elevated levels of AST and ALT and presence of antiHBcIgM.
(a) What is the probable clinical diagnosis.
(b) Which phase is the patient in.
(c) What are the common etiological agents for a similar condition.
(d) In the above case scenario, what are the other serological investigations
required.
(e) How does one get this infection.
(f) What is the long-term concern in this infection.
(g) How does one prevent this infection. Give details.
(1+1+2+2+2+2+5)
2. A 20-year-old woman came to the Medicine OPD with history of fever, fatigue and
abdominal discomfort since 4 days. It did not resolve with antipyretics. Samples were
collected for the common probable causes of this condition and was confirmed as
typhoid fever.
(a) What are the common probable causes of the above case scenario.
(b) Which is the confirmatory test for typhoid fever.
(c) What is the most important instruction to be given for sample collection for the
above test.
(d) How does one get this infection.
(e) Who is a chronic carrier of typhoid. In whom is chronic carriage likely.
(f) How to detect chronic carriers. Give details.
(g) What is the public health importance of detecting a chronic carrier.
(h) Define Multi drug resistant Salmonella Typhi.
(i) How to prevent typhoid infection.
(2+1+1+1+2+3+1+1+3)
(PTO)
Short essays
(5x8=40)
3. Quantitative buffy coat examination? principle, applications, advantages and
Disadvantages.
(3+1+2+2)
4. Describe the indications and different methods of blood culture. Discuss sample
collection for blood culture.
(3+2+3)
5. Antimicrobial susceptibility testing methods ? types with respective principle,
interpretation, purpose of selective reporting. (4+3+1)
6. Discuss mechanisms of innate immunity.
7. List antigen presenting cells and discuss their role in immune response.
Short answers
(5x4=20)
8. List four parasitic infections especially seen in immunocompromised patients.
9. Laboratory diagnosis of invasive candidiasis.
10. Importance of biofilms in management of infections.
11. List the various roles of Cell mediated immunity with specific examples.
12. Healthcare associated infections ? definition, major types, four micro-organisms
transmitted through contact.
(1+1+2)
Objective type questions
(10x1=10)
13. What is the mode of transmission of visceral leishmaniasis.
14. Which is the microbe causing lymphatic filariasis.
15. What is the stage in the life cycle of trypanosomes infective to Man.
16. What are dimorphic fungi.
17. Clinical importance of plasmids in bacteria with two examples.
18. List FOUR clinical clues associated with anaerobic infections.
19. What is the role of memory cells in immune response.
20. What is mucosal immunity.
21. Name the disinfectant (with %) to be used for a large spill.
22. Name two narrow spectrum antibiotics.
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This post was last modified on 18 November 2023