Download KUHS MBBS 2nd Year 202001 October 2022 Pharmacology Paper II Question Paper

2010 Scheme

Q.P. Code: 202001 Reg. no.: ........................

Second Professional MBBS Degree Supplementary Examinations

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October 2022

Pharmacology - Paper II

Time: 2 Hours Max. Marks: 40

• Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers
• Indicate the question number correctly for the answer in the margin space

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• Answer all parts of a single question together Leave sufficient space between answers
• Draw table/diagrams/flow charts wherever necessary

Essays (2x6=12)

1. Enumerate the second generation fluoroquinolones. What is their mechanism of action. What are the adverse effects produced by them. (2+2+2)
2. Mr. Madhavan aged 40 yrs developed pulmonary tuberculosis and he was given treatment with first line anti-tubercular agents. After one month of regular treatment, he reported back with complaints of visual disturbances and difficulty in following traffic signals.
   • Which drug is responsible for his complaints

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   • What is the mechanism of its action in tuberculosis
   • What is MDR-TB
   • How will you manage MDR-TB (1+2+1+2)

Short Notes (5x3=15)

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3. Carbimazole
4. Dipeptidyl Peptidase 4 inhibitors
5. Lansoprazole
6. Vancomycin
7. Metronidazole

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Write the Pharmacological basis for the use of: (3x1=3)

8. Mifepristone in termination of pregnancy
9. Alendronate in osteoporosis management
10. Primaquine in Vivax malaria

Write two uses and two adverse effects of the following: (3x1=3)

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11. Prednisolone
12. Griseofulvin
13. Ivermectin

Choose the appropriate drug and Justify: (2x1=2)

14. Ondansetron/Domperidone in chemotherapy induced vomiting.

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15. Methotrexate / Cisplatin in choriocarcinoma

Name the following (Two examples for each) (5x1=5)

16. Drugs for urinary tract infection
17. Antidote for iron poisoning
18. Post-exposure prophylaxis in HIV infection

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19. Anabolic steroids
20. Drugs for prevention of rejection of organ transplantation

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