Download RGUHS MBBS 1st Year 1022 RGUHS MBBS Physiology Paper I RS4 2023 April Question Paper

QP CODE: 1022

Rajiv Gandhi University of Health Sciences, Karnataka

MBBS Phase- I(CBME) Degree Examination-29-Apr-2023

--- Content provided by‍ FirstRanker.com ---

Time: Three Hours Max. Marks: 100Marks

PHYSIOLOGY- PAPER-I(RS-4)

Q.P.CODE: 1022

(QP contains two pages)

Your answers should be specific to the questions asked

--- Content provided by⁠ FirstRanker.com ---

Draw neat, labeled diagrams wherever necessary

LONG ESSAYS 2x10=20Marks

1. Define cardiac output. Explain in detail the factors regulating cardiac output. Add a note Fick's principle
2. Enumerate different types of chemo receptors. Explain their role in chemical regulation of respiration. Add a note on breath holding

SHORT ESSAYS 8x5=40 Marks

--- Content provided by‍ FirstRanker.com ---

3. Explain the intrinsic mechanism of blood clotting
4. Discuss the characteristic features of coronary circulation
5. Explain the counter current multiplier system in kidney
6. Discuss the mechanism of cell mediated immunity
7. A male aged 55 years was brought to emergency department with history of retro sternal pain since morning, pain in epigastrium radiating to left shoulder, profuse sweating. He is a known diabetic and hypertensive on irregular treatment
   1. What is the probable diagnosis?

   --- Content provided by⁠ FirstRanker.com ---

   2. What are the expected ECG changes in this condition?
   3. Why is the subendocardium more prone to Ischaemia?
8. With a neat labelled diagram, explain the different lung volumes and capacities
9. Discuss the functions of exocrine pancreatic juice and its regulation

--- Content provided by​ FirstRanker.com ---

10. Explain the micturition reflex and its higher control

SHORT ANSWERS 10x3=30 Marks

11. What is ejection fraction? Mention its clinical significance
12. Explain the significance of Timed Vital Capacity
13. Explain the physiological basis of anaemia in kidney disease

--- Content provided by‌ FirstRanker.com ---

14. List the functions of saliva
15. Explain the genesis of resting membrane potential
16. Explain type I hypersensitivity reaction
17. Explain the physiological basis of lactose intolerance
18. Enumerate the functions of lymph

--- Content provided by​ FirstRanker.com ---

19. What is respiratory acidosis? Mention one condition causing it
20. Explain the pathophysiology of peptic ulcer

Multiple Choice Questions 10x1=10 Marks

21. The pacemaker potential is due to:
    1. Fast Na+ channel
    2. Na+ entry through funny channels

    --- Content provided by FirstRanker.com ---

    3. Slow Ca++ efflux
    4. Rapid repolarization
22. True regarding endothelin-1 is all EXCEPT
    1. Broncho dilatation
    2. Vasoconstriction

    --- Content provided by‌ FirstRanker.com ---

    3. Decreased GFR
    4. Local regulation
23. Measurement of anatomic dead space is by:
    1. O2 breath test
    2. Helium dilution test

    --- Content provided by FirstRanker.com ---

    3. N2 breath test
    4. PCO2
24. Oxygen therapy is least useful in:
    1. Anaemia
    2. ARDS

    --- Content provided by⁠ FirstRanker.com ---

    3. Alveolar damage
    4. COPD
25. In renal disease albumin appears in urine because:
    1. Of its high concentration in plasma
    2. Negative charges in the glomerular wall are dissipated

    --- Content provided by⁠ FirstRanker.com ---

    3. High albumin: globulin ratio
    4. Tubular epithelial cells are sensitive to albumin

22. Which of the following does not form a filtration barrier in nephrons:
    1. Podocytes
    2. Mesangium

    --- Content provided by‍ FirstRanker.com ---

    3. Endothelial cell
    4. Basement membrane
23. Clathrin is used in:
    1. Receptor mediated endocytosis
    2. Exocytosis

    --- Content provided by​ FirstRanker.com ---

    3. Cell to cell adhesion
    4. Plasma membrane
24. Major regulator of inter digestive myo-electric complexes:
    1. VIP
    2. GIP

    --- Content provided by‍ FirstRanker.com ---

    3. Motilin
    4. Neurotensin
25. Equilibrium potential for an ion is calculated by using:
    1. Gibbs - Donnan equilibrium
    2. Nernst equation

    --- Content provided by​ FirstRanker.com ---

    3. Goldman equation
    4. Donnan equilibrium
26. Glycosylated haemoglobin is known to be a good indicator of:
    1. Blood cholesterol levels
    2. Blood triglyceride levels

    --- Content provided by FirstRanker.com ---

    3. Plasma protein levels
    4. Blood glucose levels

FirstRanker.com

--- Content provided by​ FirstRanker.com ---