Download RGUHS (Rajiv Gandhi University of Health Sciences) A Bachelor of Medicine, Bachelor of Surgery (MBBS) 1st Year (First Year) 1024 RGUHS MBBS Biochemistry Paper I RS4 2023 May Previous Question Paper || RGUHS MBBS first year question papers
QP CODE : 1024
Rajiv Gandhi University of Health Sciences, Karnataka
MBBSPhase? I(CBME)DegreeExamination-04-May-2023
Time:ThreeHours
Max.Marks:100Marks
BIOCHEMISTRY? PAPERI(RS-4)
QPCode:1024
(QPcontainstwopages)
Youranswersshouldbespecifictothequestions asked
Drawneatlabeled diagrams wherevernecessary
LONGESSAYS
2x10=20Marks
1.
A 10-year-old boy was admitted to a hospital with a diagnosis of malaria. He was started on primaquine and
antipyretics. Withinonedayhewasfoundtohavedevelopedhemolyticanemia.
a) Namethepathwayaffectedintheabovecaseand writetheenzymedefectinthepathway.
b) Namethecompounds formedinthis pathwayandwritetheirimportance.
c) Whatis therelation betweenprimaquineandhemolyticanemia?
2.
Describe cholesterol biosynthesis up to the formation of mevalonate. Explain the regulation of cholesterol
biosynthesis. Mention twocausesof Hypercholesterolemia.
SHORTESSAYS
8x5=40Marks
3.
An8-year-oldgirlpresented withdifficultyinvisionduringnighttime.VitaminAdeficiencywas suspected
fol owingexamination.
a) WritetheprovitaminformofVitaminA
b) ExplainWald' svisualcycle
4.
A 20-year-old pregnant woman presented with history of fatigue. Her peripheral blood smear showed
microcytichypochromicanemia.
a) Whichmineraldeficiencyleadstothistypeofanemia?
b) Explaintheabsorption,transportandstorageofthis mineral.
5.
Describetheroleofdietaryfibreinnutrition.
6.
Statechemiosmotictheoryand il ustratetheprocess ofoxidativephosphorylation.
7.
Define metabolic acidosis. Enumerate the causes for metabolic acidosis. Write the compensatory
mechanisminmetabolicacidosis.
8.
Describetheroleofanyfiveplasmaenzymesinthediagnosisofdisease.
9.
Explainniacinunderthefol owing headings:
a) Dietarysources
b) Co-enzymeforms
c) Deficiencymanifestation
10.
Explainthemetabolicchangesinstarvation.
SHORTANSWERS
10x3=30Marks
11.
Writethecompositionand functionsofcol agen.
12.
Enumerate the biomarkers used in the diagnosis of myocardial infarction (MI). Which biomarker is considered
specificforMIandwhy?
13.
Namethreefunctionsof thevitaminwhosedeficiencycausesscurvy.
14.
Namethreemucopolysaccharidesandwritetheirfunctions.
15.
Namethreephospholipidsand writetheirbiological importance.
16.
Mentiontwocauses ofhypokalemia. Writebiological referenceintervalforserumpotassium.
17.
DefineKm. Explainitsimportancewithanexample.
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QP CODE : 1024
Rajiv Gandhi University of Health Sciences, Karnataka
18.
Mentiontheroleofcarnitinein-oxidation.
19.
Writebiologicalimportanceofselenium.
20.
Defineactivetransport. Givetwoexamplesforactivetransport.
MultipleChoiceQuestions
10x1=10Marks
21 i)
Al thefol owinglipidsarepresentinthecel membranesEXCEPT
A. Lecithin
B. Cholesterol
C. Sphingomyelin
D. Triacylglycerol
21 i )
Whichofthefol owing derivativeofmonosaccharideis used toreduceraised intra-cranialpressure?
A. Sorbitol
B. Dulcitol
C. Ribitol
D. Mannitol
21i i)
Enzymeswhicharesynthesizedinaninactiveformarecal ed
A. Apoenzyme
B. Proenzymes
C. Coenzyme
D. Isozyme
21iv)
Theproductofglycolysisinerythrocytes is
A. Lactate
B. Pyruvate
C. Urate
D. Acetate
21 v)
Thevitamin thatactsas acoenzymefortransketolaseactivityis
A. Pyridoxine
B. Thiamine
C. Biotin
D. Folate
22 i)
Normalbiologicalreferenceintervalforserumsodiumis
A. 96-105meq/L
B. 116-135meq/L
C. 136-145meq/L
D. 156-165meq/L
22 i )
Numberofcalories givenbyonegramofcarbohydrateis
A. 2
B. 4
C. 6
D. 9
22i i)
Nitrogenousbaseethanolamineis presentin
A. Phosphatidyl inositol
B. Plasmalogen
C. Cephalin
D. Lecithin
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QP CODE : 1024
Rajiv Gandhi University of Health Sciences, Karnataka
22iv)
Theratioofbicarbonatetocarbonicacid inbicarbonatebuffersystemis
A. 20:1
B. 10:1
C. 4:1
D. 1:1
22 v)
Whichofthefol owing doesnotincreasetheabsorption ofcalcium?
A. VitaminD
B. Absenceofbilesalts
C. Basicaminoacids
D. Acidity
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This post was last modified on 18 November 2023