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QP CODE: 1022
Rajiv Gandhi University of Health Sciences, Karnataka
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MBBS Phase- I(CBME) Degree Examination-09-Feb-2023
Time: Three Hours
Max. Marks: 100Marks
PHYSIOLOGY- PAPER-I(RS-4)
Q.P. CODE: 1022
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(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2x10=20Marks
- Discuss the cardiorespiratory changes seen in a person doing moderate isotonic exercise
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Or - Define Blood Pressure. List the factors regulating blood pressure. Add a note on long term regulation of blood pressure
2. Explain the mechanism of HCL secretion in gastric juice and discuss the factors regulating it
SHORT ESSAYS 8x5=40 Marks
- Explain the pressure changes in the lung during normal respiration
- Explain the organization of body fluids compartments. Mention one method to measure extra cellular fluid volume and total body water
- Discuss the factors regulating glomerular filtration
- A 20-year-old male was brought to the casualty following a road traffic accident. On examination his extremities were found to be cold and clammy, heart rate 102/min and blood pressure 70/50mm of Hg
a) Explain the physiological basis of cold clammy extremities
b) Classify shock and state Marey's law - Explain the intrinsic mechanism of coagulation
- Explain the Bohr effect and Haldane effect
- Discuss the mechanism of fat digestion and absorption in gastrointestinal tract
- Describe the buffer systems present in renal tubules
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SHORT ANSWERS 10x3=30Marks
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- Mention the physiological basis of increased ventilation perfusion ratio in apex of lung
- Classify anaemia on the basis of morphology with examples
- Mention the causes for the waves of Jugular venous pulse
- List different layers of respiratory membrane
- Explain the basis of using phototherapy for physiological jaundice
- Explain the basis of megaloblastic anemia seen after gastrectomy
- Enumerate the function of platelets
- Explain Laplace law with reference to urinary bladder
- List the properties of cardiac muscle
- Explain the mechanism of action of loop diuretics
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Multiple Choice Questions 10x1=10 Marks
- i) Cephalic phase of gastric juice secretion is controlled mainly by
A. Neural factors
B. Hormonal factors
C. Gastric distension--- Content provided by FirstRanker.com ---
D. Presence of proteins in stomach - ii) Atrial systole coincides with ventricular
A. Isometric contraction
B. Rapid ejection phase
C. Last rapid filling phase--- Content provided by FirstRanker.com ---
D. Isometric relaxation - iii) Descending limb of loop of Henle is permeable to all EXCEPT
A. Water
B. Sodium
C. Urea--- Content provided by FirstRanker.com ---
D. Glucose - iv) PCO2 of alveolar air in mm of Hg
A. 104
B. 46
C. 40--- Content provided by FirstRanker.com ---
D. 27 - v) Maximum velocity of conduction in the cardiac musculature is seen in
A. SA node
B. AV node
C. Bundle of His--- Content provided by FirstRanker.com ---
D. Purkinje fibers - Edema can develop due to
A. Decrease in capillary hydrostatic pressure
B. Increase in interstitial fluid hydrostatic pressure
C. Decrease in capillary oncotic pressure--- Content provided by FirstRanker.com ---
D. Decrease in interstitial fluid colloid osmotic pressure - ii) The plasma level at which a substance first appears in urine is
A. Renal threshold
B. Renal clearance
C. Tubular maximum--- Content provided by FirstRanker.com ---
D. Filtered load - iii) Chief cells of gastric gland secrete
A. Hydrochloric acid
B. Mucous
C. Pepsinogen--- Content provided by FirstRanker.com ---
D. Intrinsic factor - iv) Decompression sickness is due to
A. Increased partial pressure of nitrogen in alveolar air
B. Bubbling of CO2 in tissues
C. Decreased PO2 in atmospheric air--- Content provided by FirstRanker.com ---
D. Nitrogen bubbles in body fluids - v) Warfarin acts as an anticoagulant by decreasing
A. Calcium content in blood
B. Active form of vitamin K
C. Thrombin level--- Content provided by FirstRanker.com ---
D. Platelet aggregation
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