Download (Rajiv Gandhi University of Health Sciences) A Bachelor of Medicine, Bachelor of Surgery (MBBS) 1st Year (First Year) 1024 RGUHS MBBS Biochemistry Paper I RS4 2023 Feb Previous Question Paper || RGUHS MBBS first year question papers
QP CODE : 1024
Rajiv Gandhi University of Health Sciences, Karnataka
MBBSPhase? I(CBME)DegreeExamination-14-Feb-2023
Time:ThreeHours
Max.Marks:100Marks
BIOCHEMISTRY? PAPERI(RS-4)
QPCode:1024
(QPcontainstwopages)
Youranswersshouldbespecifictothequestions asked
Drawneatlabeled diagrams wherevernecessary
LONGESSAYS
2x10=20Marks
1.
A medical student whohad an examon the nextday did not eat anything the previous night. Nextday morning,
hehad severeheadacheand giddinessbeforeexam. Hisfastingplasmaglucosewas 48mg/dl.
a) Interprettheplasmaglucosevalue
b) Namethemetabolicpathways whichmaintain blood glucoseinfasting state
c) Explain themetabolicpathwaythatsynthesiseglucosefrompyruvate
2.
MentiontheactiveformofVitaminD.Describethesynthesis,biochemical functionsandRDAof VitaminD.
SHORTESSAYS
8x5=40Marks
3.
A 48-year-old man diagnosed with myocardial infarction (MI) had an altered lipid profile with elevated total
cholesteroland LDLcholesterol.
a) WritethebiologicalreferenceintervalofLDLcholesterol.
b) ExplaintheformationofLDLcholesterol.
c) ReasonoutwhyLDLcholesterolisatherogenic.
4.
A 70-year-old man suffered an attack of pneumonia. He found it difficult to breathe and was losing
consciousness. His Arterial Blood Gas (ABG) report was as fol ows: pH=7.1,
pCO2 = 52 mmHg, Plasma
Bicarbonate(HCO3-)=25meq/L.
a) InterprettheABGreport.
b) Writethecompensatorymechanismin theaboveacid-basedisorder.
5.
Mentionbiologicalreferenceintervalforserumcalcium. Describeanyfourfunctions ofcalcium.
6.
DefineIsoenzymes.MentiontheIsoenzymes ofcreatinephosphokinase(CPK)andwritetheirsignificance.
7.
DefineBasalMetabolicRate(BMR).EnumeratethefactorsaffectingBMR.
8.
Explainthemetabolicadaptationsinwel -fed state.
9.
Explaincompetitiveinhibitionofenzymeswithtwoexamples.
10.
Explainthefunctionsof peroxisomesand describetheirroleinfattyacid oxidation.
SHORTANSWERS
10x3=30Marks
11.
Whatisfattyliver?Mentionanytwolipotropicfactors.
12.
Whatishyponatremia?Listtwocausesofhyponatremia.
13.
Component of oral rehydration solution (ORS) has sodium chloride and glucose. What is purpose of adding
glucoseinORS?
14.
Mentionanythreesitespecificinhibitors ofelectrontransportchain.
15.
NametheenzymedefectinvonGierke' s disease. WritethebiochemicalalterationsinvonGierke' sdisease.
16.
Whatisthecauseofpel agra?Writetheclinicalmanifestationsofpel agra.
17.
Adiabeticpatientwas advisednottotakepolished ricebuttotakebrownrice.Explainthereasonsforthesame.
18.
Mentionthreehomopolysccharidesof glucoseand writetheirbiologicalimportance.
19.
WritethebiochemicaldefectinEhlerDanlosSyndromeand Osteogenesisimperfecta.
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QP CODE : 1024
Rajiv Gandhi University of Health Sciences, Karnataka
20.
Writethebiochemicalcauseofrespiratorydistress syndromeinprematurebabies.
MultipleChoiceQuestions
10x1=10Marks
21 i)
Hexokinasebelongstowhichclassofenzymes?
A. Oxidoreductase
B. Transferase
C. Hydrolase
D. Lyase
21 i )
Whichofthefol owing vitaminsis usedintheelectron transportchain?
A. Riboflavin
B. Pantothenicacid
C. Pyridoxine
D. Biotin
21i i)
Glucoseandfructosearemonosaccharideunitsof
A. Lactose
B. Maltose
C. Sucrose
D. Isomaltose
21iv)
Thesugarcomponentofcerebrosideis
A. Galactose
B. Lactose
C. Fructose
D. Ribose
21 v)
ThenormalAniongap is
A. 4-8 mmol/L
B. 10-14 mmol/L
C. 16-20 mmol/L
D. 22-26 mmol/L
22 i)
Limitingaminoacidintheproteingelatinis
A. Lysine
B. Threonine
C. Tryptophan
D. Methionine
22 i )
Whichcoenzymeisresponsibleforcarboxylation reactions
A. Biocytin
B. FAD
C. NAD
D. TPP
22i i)
Hormoneinsulinactivateswhichof thefol owing pathway
A. Glycogenolysis
B. Gluconeogenesis
C. Glycolysis
D. Lipolysis
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QP CODE : 1024
Rajiv Gandhi University of Health Sciences, Karnataka
22iv)
InWilson' s diseasecopperaccumulatesinal ofthefol owing tissues EXCEPT
A. Eyes
B. Spleen
C. Brain
D. Liver
22 v)
Themarkerenzymeformicrosomesis
A. ATPsynthase
B. Cathepsin
C. Glucose-6-phosphatase
D. Lactatedehydrogenase
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This post was last modified on 18 November 2023