Download RTMNU B.Pharma 6th Semester 2016 Winter Clinical Pharmatherapeutics Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 6th Semester 2016 Winter Clinical Pharmatherapeutics Question Paper

B.Pharm. Semester?VI (C.B.S.) Examination
CLINICAL PHARMACOTHERAPEUTICS?I
Paper?S (6T5)
Time : Three Hours]
N.B. :? (1)
(2)
(3)
(4)
(5)
(6)
Question N0. 1 is compulsory.
Solve any F OUR questions from the remaining.
Draw neat labelled diagram wherever necessary.
Discuss the reaction, mechanism wherever necessary.
Use of electronic calculator is permitted.
Assume suitable data wherever necessary.
1. Solve any ?ve of the following :
KNT/KW/16/6574
[Full Marks : 80
(a) What is essential drug concept ? Explain with suitable examples. 4
(b) Write down the etiopathogenesis of cystic fibrosis and suggest suitable therapy for it. 4
(c) What is rational drug formulations ? Describe with suitable examples. 4
(d) What is the pathogenesis of acute renal failure ? Give outline for its immediate treatment. 4
(e) J ustify the use of Carbidopa and Levodopa combination in parkinsonism 4
(f) Give the rationale for combination of proton pump inhibitor and porokinetic agents in the treatment
of GERD.
4
(g) Explain the mechanism of action, pharmacokinetics, uses and adverse effects Monteleukast. 4
2. Explain various factors involved in etiopathogenesis of hypertension. Give classification, mechanism of
action, adverse effects and speci?c clinical indications of anti-hypertensive drugs. 15
3. (21) Describe various in?ammatory mediators asthma. J ustify importance of cyclic Amp activators in its
treatment.
(b) What is Systemic Lupus erythematin ? Give its pharmacotherapy.
NVM?6946
10
5
(Contd.)

4. Give detailed pharmacological account of drugs used in the treatment of hyperlipidaemias. Add a note on
obesity and associated complications. 15
5. (a) Explain pathophysiological aspects and typical symptoms of congestive heart failure. Describe mechanisms
of action, pharmacokinetic, adverse effects and therapeutic uses of digitalis. 10
(b) Describe the pathogenis and treatment of Hepatitis B. 5
6. (a) What are the different types of anemias, compare their pathological aspects ? 5
(b) Explain the pharmacological importance ofAllopurinol in the treatment of Gout. 5
(c) J ustify the importance of Quetiapine in the tratement of depression. 5
7. Write a brief note on pathogenesis and treatment of any three of the following :
(a) Rheumatoid arthritis
(b) Chronic obstructive pulmonary diseases
(c) Alzheimer?s diseases
((1) Spondylitis
(e) Angina pectoris. 3 X5=1 5
NVM?6946 KNT/KW/16/6574