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NRJ/KW/17/4292
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B.Pharm. Seventh Semester (C.B.S.) Examination
PHARMACEUTICAL MEDICINAL CHEMISTRY-III
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Paper-2
Time: Three Hours]
[Maximum Marks : 80
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N.B. :— (1) Question No. 1 is compulsory.
(2) Attempt any four questions out of remaining.
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(3) Draw neat labeled diagram wherever necessary.
- Solve any FIVE from the following :
- Explain cardiotonics with examples.
- Write chemical name and synthesis of guanethidine monosulphate.
- Discuss about oral contraceptives.
- Explain biogenesis of adrenergic neurotransmitters and write about role of alpha methyl tyrosine.
- Discuss about neuromuscular blockers.
- Write use, chemical name and synthesis of Hydrochlorthiazide.
- Explain nitrovasodilators with examples.
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5×4=20
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- Explain about action potential of cardiac muscles. Write in detail about chemical classification and mechanism of action of antiarrythmic agents.
15
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- Give the chemical classification of Diuretics.
7
- Write note on anticoagulant and thrombolytic agents.
8
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- Give the chemical classification of Diuretics.
- Explain stereochemistry of steroids. Write in detail about SAR with examples of adrenocorticoids.
15
- Write in detail about chemical classification and uses of acetylcholinesterase inhibitors. Write short note on antispasmodics.
15
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- Discuss in detail about estrogens and progestational agents.
8
- Write note on adrenoreceptor blockers and write synthesis of Atenolol hydrochloride.
7
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- Discuss in detail about estrogens and progestational agents.
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- Explain statins and other agents as antihyperlipidemics.
8
- Discuss SAR of androgens.
7
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- Explain statins and other agents as antihyperlipidemics.
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?-27559
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