Download RTMNU B.Pharma 4th Semester 2016 Summer Pharmaceutical Chemistry 4 (Heterocyclic And Macromolecules) Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 4th Semester 2016 Summer Pharmaceutical Chemistry 4 (Heterocyclic And Macromolecules) Question Paper

TKN/KS/16/6988
B.Pharm. Semester?IV (C.B.S.) Examination
PHARMACEUTICAL CHEMISTRY?IV
(Heterocyclic and Macromolecules)
Paper?Z (4T2)
Time?Three Hours] [F ull Marks?80
N.B. :? (1) Question N0. 1 is compulsory.
(2) Solve any F OUR questions from the
remaining.
(3) Draw neat labeled diagram wherever
necessary.
(4) Discuss the reaction, mechanism
wherever necessary.
(5) Assume suitable data wherever
necessary.
1. Solve any FIVE 0f the following :
(a) De?ne Saponi?cation Value and Iodine Value with
its signi?cance.
(b) Write the biological importance of heterocycles in
medicinal chemistry.
(0) Write the chemical propetties 0f Pyrimidine.
MXP?N?37 1 6 1 Contd.

(d)
(e)
(f)
(g)
(b)
(b)
(b)
(b)
Write a note on mutarotation phenomenon in
Carbohydrates.
Pyridine is more basic than Pyrrole. Explain.
Differentiate between fats, oils and waxes.
Why Pyrrole undergoes electrophilic substitution
reaction of C?2 position ? 4X5=20
What are heterocyclic compounds ? Discuss in detail
about chemistry, properties and synthesis of Pyridine.
8
Discuss the reaction and mechanism of Skroup's
synthesis of Quinoline. 7
Discuss the structure and synthesis of Naphthalene.
8
Write the chemical properties of Naphthalene. 7
De?ne and classify carbohydrates giving suitable
examples with structure. Add a note on cyclic structure
of D?glucose. 8
Describe in detail about Killiani-Fischer synthesis
and Ruffs degradation method. 7
De?ne and classify Amino acids with suitable structure.
Give any one method for amino and carbonyl end
degradation of amino acid. 8
Discuss the secondary structure of proteins. 7
MXP?N?37 1 6 2 Contd.
6.
(a)
(b)
Define and classify Lipids. Explain various
phannacopoeial standards to check purity of oil.
8
Write a note on Phospholipids. 7
Attempt the following (any THREE) :
(a)
(b)
(C)
(d)
(e)
Fischer?Indole Synthesis
Chemistry of Maltose
Bischler?Napierolski reaction of Isoquinoline
Chichibabin reaction
Structure of Amygdalin. 15
MXP?N?37 1 6 3 1250