Download RTMNU B.Pharma 4th Semester 2016 Winter Pharmaceutical Microbiology and Immunology 2 Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 4th Semester 2016 Winter Pharmaceutical Microbiology and Immunology 2 Question Paper

KNT/KW/l6/6562
B.Pharm. Fourth Semester (C.B.S.) Examination
PHARMACEUTICAL MICROBIOLOGY AND IMMUNOLOGY?II
Paper?S (4 T 5)
Time : Three Hours]
N.B. :? (1) Question N0. 1 is compulsory.
(2) Solve any FOUR questions from the remaining.
(3) Draw neat labelled diagram wherever necessary.
1. Solve the following (any FIVE) :
(a)
(b)
(C)
(d)
(e)
(f)
(5;)
Explain D value and Z value.
Discuss the method of evaluation of disinfectant by Rideal Walker Test.
Explain in?ammation and defense mechanism of host.
Write in short about laminar air?ow unit.
Discuss the tuberculin test.
Give the method of preparation of tetanus toxoid.
Explain the compliment proteins.
[Full Marks : 80
5X4=20
2. Define antigen and antibodies and give a detailed account of various antigen antibody reactions.
3. (a)
(b)
Define hypersensitivity and explain its types in detail.
Comment on sterility testing of pharmaceutical products as per LP.
4. Discuss the methods of preparation of :
(a)
(b)
(C)
BCG vaccine
Smallpox vaccine
DPT vaccine.
NVM?6940
15
10
5
15
(Contd)

5. Define sterilisation. Discuss the various methods of sterilisation used in pharmaceutical industry with
their advantages and limitations. 15
6. Differentiate between :
(a) Vaccines and Sera
(b) Endotoxins and Exotoxins
(0) Active immunity and Passive immunity. 15
7. Write short notes on (any two) :
(a) Sterilisation indicators
(b) Sources of contamination in aseptic area
(0) Disinfectants. 15
NVM?6940 KNT/KW/ 16/6562