Download OU M.Pharma Ph.Chemistry 1st Sem 2020 6110PCI Advanced Organic Chemistry I Question Paper

Download OU (Osmania University) M.Pharma-Ph.Chemistry (Master of Pharmacy) 1st Sem 2020 6110PCI Advanced Organic Chemistry I Previous Question Paper

- -
Code No: 6110/PCI
M. Pharmacy (Pharmaceutical Chemistry) I-Semester (PCI) (Main & Backlog)
Examination, February 2020

Subject: Advanced Organic Chemistry-I
Time: 3 Hrs Max. Marks: 75

Note: Answer any Five questions. All questions carry equal marks.

1 a) Explain the structure and stability of carbocations and carbanions. 8M
b) Discuss SN
reactions with mechanism and stereo chemistry. 7M

2 a) Enlist the types of rearrangement reactions and discuss the mechanisms of any
b) Explain the mechanism of E1 elimination with examples. (9+6)

3 Discuss the mechanism and applications of any three named reactions 15M
a) Sandmayer reaction
b) Sharpless Epoxidation
c) Michael reaction
d) Mannich reaction

4 Write abt reaction mechanism and synthetic applications of
a) Mitsunobu reaction and Mannich reaction.
b) Baeyer-Villiger oxidation and Doebner-Miller Reaction. (8+7)

5 Write the preparation and synthetic applications of any three of the following
a) Diazomethane
b) Aluminium isopropoxide
c) Dicyclohexyl carbodimide
d) Wilkinsons reagent (15)

6 a) Give an accnt of protection of Amine and Carboxyl grps and the ir synthetic
b) Give the reaction and explain mechanism of Knorr pyrazole synthesis and
combes quinoline synthesis. (5+10)

7 tline the synthesis of following
a) Celecoxib
b) Ketoconazole
c) Chloroquine (15M)

8 a) Explain C-C disconnection of alcohols and carbonyl compnds.
b) Discuss the retro synthetic strategies for Five and six membered ring systems. (8+7)

************ - FirstRanker's Choice

This post was last modified on 19 July 2020