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Code No: 6103/PCI
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FACULTY OF PHARMACY
M.Pharmacy (pharmaceutics) I-Semester (PCI) (Main & Backlog) Examination, February 2020
Subject: Drug Delivery System
Time: 3hrs Max Marks: 75
Note: Answer any five questions, all questions carry equal marks.
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- Explain physiochemical and biological approaches for designing SR formulations? (15)
- What do you mean by personalized medicines? Describe in detail bioelectronic medicines and telepharmacy. (15)
- Explain the principles of rate controlled drug delivery systems? Write a note on osmotically controlled drug delivery systems? (15)
- a) Mention different types of gastroretentive drug delivery system? Mention its advantages and disadvantages? (5)
b) Describe in detail buccal drug delivery system? (10) - Explain the principles and theories of mucoadhesion? Add a note on mechanisms of mucosal drug permeation? (15)
- a) Describe barriers of ocular drug delivery system and what are methods to overcome the same? (8)
b) Write a note on transdermal permeation enhancers? (7) - What are the barriers of protein drug delivery? Explain various modified formulations of proteins and peptides to overcome the absorption barriers? (15)
- What are the advancements in vaccine delivery systems? Explain transdermal delivery of vaccines? (15)
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