Download OU M.Pharma Ph.Analysis 2nd Sem 2019 13336PCI Modern Bio Analytical Techniques Question Paper

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Code No: 13336/PCI

FACULTY OF PHARMACY

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M. Pharmacy (Pharma Analysis) II- Semester (PCI) (Main) Examination, Aug. 2019

Subject: Modern Bio Analytical Techniques

Time: 3 Hrs Max Marks: 75

Note: Answer Any Five Questions. ALL Questions carry Equal Marks.

1. a) What is the importance of extraction of drugs and metabolites from biological matrices?
   

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   b) Describe the bioanalytical method procedure for liquid and solid phase extraction? 15
2. a) Mention the different alternative methods of dissolution testing transport models 11
   b) Define solubility & permeability based on biopharmaceutics classification system. 4
3. Describe various drug interaction (PK - PD) interactions)? 15
4. Discuss the principles and applications of flow cytometry. 15

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5. Write the different methods for the assessment of bioavailability and bioequivalence? 15
6. a) Explain the drug permeability by in-vivo method? 8
   b) Write notes on cross over design. 7
7. Write notes on the following
   a) Drug interaction linked to transporters. 8
   

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   b) Cryopreservation techniques. 7
8. Discuss about the design and evaluation of bioequivalence studies. 15

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