Download OU M.Pharma Ph.Chemistry 2nd Sem 2020 6113PCI Advanced Spectral Analysis Question Paper

Download OU (Osmania University) M.Pharma-Ph.Chemistry (Master of Pharmacy) 2nd Semester 2020 6113PCI Advanced Spectral Analysis Previous Question Paper

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Code No. 6113/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) II-Semester (PCI) (Suppl.) Examination,
January 2020

Subject: Advanced Spectral Analysis
Time: 3 Hrs Max. Marks: 75

Note: Answer any five questions. All questions carry equal marks.

1 (a) Explain Woodward Fieser rules for ?, ?-carbonyl compnds and 1,3 -butadienes
and calculate the ? max for the following.
i) ii) iii)
(b) How do y interpret the following fu nctional grps in IR
(i) -OH (ii) Ar-NH2 (iii) - C=O (iv) ?COOH (v) -CN vi) ?Cl ? (9+6)

2 Draw schematic 1-D & 2-D NMR spectra and explain the interpretation giving one
example. (15)

3 (a) Discuss the fragmentation pattern of varis functional grps. (8)
(b) Explain Mc-Leffety rearrangement and isotopic peaks. (7)

4 Explain the Principle, instrumentation and applications of following :
(a) HPLC (b) GC-MS (8+7)

5 (a) Explain the Principle, instrumentation and applications of LCMS.
(b) Write a note on super critical chromatography. (10+5)

6 Explain the Principle instrumentation and applications of : (7+8)
(a) DSC
(b) TGA

7 (a) Explain the bio assay of insulin
(b) Write a note on Radioimmuno assay (8+7)

8 Draw and explain the proton NMR and Mass spectra of Benzyl alcohol and 4-hydroxy
tlene (15)

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