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Rajiv Gandhi University of Health Sciences, Karnataka
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I Year Pharm-D Degree Examination - NOVEMBER 2015
Time: Three Hours
Max. Marks: 70 Marks
MEDICINAL BIOCHEMISTRY
Q.P. CODE: 2853
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Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Explain the synthesis and breakdown of glycogen.
- Explain in detail ß-oxidation of fatty acids.
- Describe the metabolism of pyrimidine nucleotides.
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SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Write in detail HMP pathway of glucose utilization.
- What is mutation? Discuss its repair mechanism.
- Name the important phospholipids and give their physiological role.
- Write a note on enzyme inhibition.
- Radioimmunoassay (RIA)
- Discuss the test to assess the metabolic and detoxification capacity of liver.
- Write a note on the uncouplers and inhibitors of oxidative phosphorylation.
- Metabolic disorders of amino acids
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SHORT ANSWERS 10 x 2 = 20 Marks
- Water balance in the body
- Hyperbilirubinemia
- Isoenzymes.
- Ketone bodies
- Galactose tolerance test
- Creatinine clearance
- Enzyme induction and repression.
- Cytochromes.
- Urinary tract calculi
- HDL and LDL
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